Midline cleft of lower lip
Overview
Median cleft of lower lip and mandible is a rare anomaly. It has also been described as Cleft No. 30 of Tessier's classification. Couronne' reported the first account of this anomaly in 1819[1]. Since then very few cases have been reported in literature with different variations. We came across a patient with associated ectopic salivary gland on the dorsum of tongue. Case History A six-month-old, first born, male child presented to us with median cleft of lower lip [Figure:1]. The tongue was attached to the mandible and cleft margins of lower lip
Causes
* Associated with various syndromes: * Branchio-oculo-facial syndrome * Ellis-van Creveld syndrome * Frontonasal malformation * Holoprosencephaly * Hydrolethalis * Orofaciodigital syndrome * Hypopituitarism * Rubella infection * Steroids
Diagnosis
* Associated with various syndromes: * Branchio-oculo-facial syndrome * Ellis-van Creveld syndrome * Frontonasal malformation * Holoprosencephaly * Hydrolethalis * Orofaciodigital syndrome * Hypopituitarism * Rubella infection * Steroids