Marinesco-Sjogren-like syndrome (MSLS)

Overview

A very rare disorder characterized by cataracts (during childhood), mental retardation, muscle weakness and brain degeneration. The disorder is very similar to another syndrome called Marinesco-Sjogren syndrome.

Symptoms

* Cerebellar atrophy * Mental retardation * Myopathy * Juvenile cataract * Muscle weakness

Causes

* Chronic hypokalemia (see Hypokalemia) * Alcoholism * Polymyositis * HIV myopathy * Cushing's syndrome * Hyperparathyroidism * Muscular dystrophy * Myotonic dystrophy * Myotonia congenita * Mitochondrial myopathy * Sarcoidosis * Medications * Arteriosclerosis * Alzheimer's disease * Encephalitis * Huntington's disease * Pick's disease