Hinson-Pepys disease
Overview
An allergic reaction to a particular fungus called Aspergillus
Symptoms
* Wheezing * Low-grade fever * Coughing * Coughing up brown-flecked masses or mucus plugs * Asthma symptoms * Dyspnea * Wheezing * Lung inflammation * Airway inflammation * Shortness of breath * Mild fever * Coughing up discolored phlegm * Coughing
Causes
The most common identifiable cause of allergic purpura is probably an autoimmune reaction directed against vascular walls, triggered by a bacterial infection (particularly streptococcal infection). Typically, upper respiratory tract infection occurs 1 to 3 weeks before the onset of symptoms. Other possible causes include allergic reactions to some drugs and vaccines, to insect bites, and to some foods (such as wheat, eggs, milk, and chocolate). Allergic purpura affects more males than females and is most prevalent in children ages 3 to 7. The prognosis is more favorable for children than adults.
Diagnosis
* Fungi skin testing, blood tests, X-rays, Fungi sputum tests
Treatment
Treatment is generally symptomatic; for example, severe allergic purpura may require steroids to relieve edema and analgesics to relieve joint and abdominal pain. Some patients with chronic renal disease may benefit from immunosuppressive therapy with azathioprine along with identification of the provocative allergen. An accurate allergy history is essential.
Resources
Hinson-Pepys disease: Another name for Allergic bronchopulmonary aspergillosis