Griscelli syndrome type 3

Overview

Griscelli syndrome type III: A rare genetic condition characterized by a partial lack of pigmentation in the eye, skin and hair, clumps of pigmentation in hair shafts and immunodeficiency.

Symptoms

Pigment clumps in hair shafts Melanosome accumulation in melanocytes Recurrent neutropenia Low blood platelet level Decreased gamma globulin levels in blood

Causes

Although the cause of CFIDS is unknown, researchers suspect that it may be found in human herpesvirus 6 or in other herpesviruses, enteroviruses, or retroviruses. Rising levels of antibodies to EBV, once thought to implicate EBV infection as the cause of CFIDS, are now considered a result of this disease. CFIDS may be associated with a reaction to viral illness that’s complicated by dysfunctional immune response and by other factors that may include sex, age, genetic disposition, prior illness, stress, and environment.

Prognosis

The 'prognosis' of Griscelli syndrome type III usually refers to the likely outcome of Griscelli syndrome type III. The prognosis of Griscelli syndrome type III may include the duration of Griscelli syndrome type III, chances of complications of Griscelli syndrome type III, probable outcomes, prospects for recovery, recovery period for Griscelli syndrome type III, survival rates, death rates, and other outcome possibilities in the overall prognosis of Griscelli syndrome type III. Naturally, such forecast issues are by their nature unpredictable.