Daish Hardman Lamont syndrome
Overview
Daish-Hardman-Lamont syndrome: A very rare syndrome characterized mainly by loose joints, tall stature and buildup of fluid inside the skull
Symptoms
* Tall stature * Loose joints * Fluid buildup inside skull * Kyphosis * Increased joint mobility
Causes
* Constitutional tall stature –Most common cause o Endocrine disorders –Excess GH secretion (pituitary gigantism) –McCune-Albright syndrome –Multiple endocrine neoplasia is associated with excess GH secretion * Precocious puberty –Tall initially –Final height compromised * Hyperthyroidism * Reduced sex steroid activity –Hypogonadism –Klinefelter syndrome –Androgen or estrogen deficiency –Estrogen resistance –Androgen insensitivity syndrome * Excess insulin –Exogenous obesity –Maternal diabetes mellitus * Cerebral gigantism (Sotos syndrome) * Weaver syndrome * Beckwith-Wiedemann syndrome * Marfan syndrome * Homocystinuria * Fragile X syndrome