Cyclosporiasis
Overview
Cyclosporiasis refers to infection by the spore-forming protozoan known as Cyclospora. Protozoa are a group of parasites that infect the human intestine. Parasites are organisms that live in another body, called the host, and get food and liquids from that host. This parasite is a member of the group of protozoa known as coccidia, to which Cryptosporidia also belongs. This group of parasites infects the human intestine, and causes chronic recurrent infections in those with altered immunity or AIDS.
Symptoms
Symptoms begin after an incubation period of about a day or so following ingestion of cysts. A brief period of flu-like illness characterized by weakness and low-grade fever is followed by watery diarrhea, nausea, loss of appetite, and muscle aches. In some patients, symptoms may wax and wane for weeks, and there are those in whom nausea and burping may predominate. It is also believed that infection can occur without any symptoms at all.
Diagnosis
The disease should be suspected in anyone with a history of prolonged or recurrent diarrhea. The parasite is identified either by staining stool specimens or by applying certain fluorescent ultraviolet techniques to find the characteristic cysts. Biopsy of an infected organ such as the intestine through an endoscope is another way to make the diagnosis.
Treatment
The first aim of treatment as with any severe diarrheal illness is to avoid dehydration and malnutrition. Oral Rehydration Solution (ORS) or intravenous fluids are sometimes needed. Medications used to treat diarrhea by decreasing intestinal motility, such as loperamide or diphenoxylate are also useful, but should only be used with the advice of a physician. The use of the medication, trimethoprim-sulfamethoxazole (Bactrim) for one week can be successful in treating intestinal infections and prevents relapse in those with a normal immune system. The same medicine can be prescribed to treat infections of both the intestine or bile ducts in immunocompromised individuals, but maintenance or continuous treatment is often needed.