Corpus callosum agenesis neuronopathy

Overview

A rare genetic disorder involving mental retardation, progressive neuropathy and absence of the fibers that connect the two halves of the brain together.

Symptoms

* Mental retardation * Physical retardation * Impaired tendon reflex * Partial paralysis of lower limbs * Small head

Causes

? Diabetes ? Alcohol ? Vitamin B12 deficiency ? Drugs ? Carcinomatous ? Lead ? Guillain-Barré ? Tabes dorsalis ? Syringomyelia ? Polyarteritis nodosa ? Amyloidosis ? Polymyositis

Diagnosis

Current diagnostic techniques involve a combination of a physical evaluation, and diagnostic instruments. When a patient has been determined to have the necessary physical features, physicians then usually turn to magnetic resonance imaging to tell whether there is agenesis of the corpus callosum or not