Ciliary dyskinesia- due to transposition of ciliary microtubules
Overview
A very rare disorder where the cilia fail to move adequately due to abnormal cilia structure. The cilia are tiny, hair-like structures found in the respiratory and ear passages and help to clear debris and mucus. This results in increases risk of respiratory infections, sinusitis, ear infections and male infertility. The infertility results as the tails of sperm is basically cilia
Symptoms
* Chronic inflammatory lung disease * Increased risk of respiratory infection * Asymptomatic * Male infertility * Increased risk of sinusitis * Increased risk of ear infections * Mouth breathing * Nasal discharge * Nasal polyps * Halitosis * Nasal congestion * Impaired hearing * Wheezing * Respiratory problems * Bronchiectasis * Headache * Chronic cough
Causes
Primary ciliary dyskinesia (PCD) is a genetic disorder, and it appears to follow the autosomal recessive inheritance pattern. Two genes directly implicated in autosomal recessive PCD are DNAI1 and DNAH5, which encode for components of the outer dynein arm complex
Diagnosis
signs and symptoms of Ciliary dyskinesia, due to transposition of ciliary microtubules may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed Ciliary dyskinesia, due to transposition of ciliary microtubules symptoms.