Chromosome 3- trisomy 3q
Overview
Chromosome 3, trisomy 3q: A rare chromosomal disorder where a portion of the long arm (q) of chromosome 3 is duplicated so there is three copies of it rather than the normal two. The condition is characterized by mental and growth deficiency, broad nose root and excessive hair growth.
Symptoms
The list of signs and symptoms mentioned in various sources for Chromosome 3, trisomy 3q includes the 48 symptoms listed below: * Severe mental retardation * Growth retardation * Broad nose * Seizures * Small head * Frontal bossing * Temporal indentation * Small jaw * Maxillary prognathism * Square face * Full cheeks * Abnormal head shape * Premature closing of skull bones * Low set ears * Malformed ear structure * Prominent philtrum * Forward tilting nostrils * High nasal bridge * Epicanthal folds * Arched eyebrows * Joined eyebrows * Upward slanting space between eyelids * Wide-set eyes * Long upper lip * High arched palate * Cleft lip * Cleft palate * Down turned mouth corners * Short neck * Webbed neck * Widely spaced nipples * Flattened chest * Clinodactyly * Brachydactyly * Camptodactyly * Tapered fingers * Excessive whorls in fingertip whorls * Excessive simian creases * Excessive hair growth * Seizures * Brain abnormalities * Reduced muscle tone * Hypoplastic nails * Heart abnormalities * Septal heart defects * Small penis * Hypospadias * Undescended testes
Causes
* Abnormal head shape * Brachydactyly * Brain abnormalities * Broad nose * Camptodactyly * Cleft lip * Cleft palate * Clinodactyly * Epicanthal folds * Excessive hair growth * Forward tilting nostrils * Frontal bossing * Full cheeks * Growth retardation * Heart abnormalities * High arched palate * High nasal bridge * Hypoplastic nails * Low set ears * Reduced muscle tone * Seizures * Seizures * Short neck * Small head * Small jaw * Small penis * Tapered fingers * Upward slanting space between eyelids * Webbed neck * Wide-set eyes * Widely spaced nipples
Diagnosis
These home medical tests may be relevant to Chromosome 3, trisomy 3q: * Cold & Flu: Home Testing: * Home Fever Tests * Home Ear Infection Tests * Home Flu Tests