CDG syndrome type 1C

Overview

A very rare inherited metabolic disorder where defective carbohydrate compounds are attached to glycoproteins and thus impairing glycoprotein function. Type 1C has a ?1,3-glucosyl-transferase enzyme defect.

Symptoms

* Psychomotor retardation * Hypotonia * Strabismus * Coagulopathy * Small head * Feeding difficulties * Ataxia * Finger abnormalities * Deep vein thrombosis * Pseudotumor cerebri * Endocrine disturbances * Hyperandrogenism * Virilization

Diagnosis

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