Brenner tumor of the vagina

Overview

Polyps of the vagina are rare and are either of inflammatory/reactive or neoplastic origin. A case of extraovarian Brenner tumour of the vagina in a postmenopausal woman, who presented with a vaginal polyp, is described. The polyp was excised and on histological examination, had the triphasic pattern (transitional, glandular and stromal) characteristic of Brenner tumour. The histogenesis of Brenner tumour is discussed in the context of this unusual location and the controversy of its origin.

Symptoms

The Brenner tumor is an uncommon ovarian tumor in pregnancy with only three previous cases in the English published reports. A 35-year-old woman delivered abdominally because of distress symptoms and a Brenner tumor was resected incidentally. Histological examination revealed a tumor composed of epithelial nests and areas of stromal luteinization. The patient was treated conservatively. Brenner tumor should be considered in the differential diagnosis of adnexal masses during pregnancy. These tumors are mainly benign and show typical luteinization associated with the hormonal milieu in pregnancy.

Causes

Ovarian cancer often causes signs and symptoms. See your doctor, nurse, or other health care professional if you have any of these signs every day for two weeks or longer and they are not normal for you, especially if they get worse: * Discomfort in the lower abdomen. * Abdominal swelling and/ or pain; bloating and/or a feeling of fullness. * Vague but persistent gastrointestinal complaints, such as gas, nausea and indigestion. * Frequency and/or urgency of urination, and frequent urinary tract infections. * Constipation. * Menstrual disorders, such as abnormal bleeding or postmenopausal bleeding. * Unexplained tiredness and fatigue. * Loss of appetite. * Shortness of breath/difficulty breathing. * Unexplained weight loss and/or weight gain. * Sudden stomach "blows up" resembling pregnancy.