Bartter syndrome- antenatal- type 1
Overview
Bartter's syndrome, antenatal type 1: A rare genetic kidney disorder that causes hypokalemia. A defect in the NKCC2 gene impairs the functioning of the Na-Cl cotransporter and leads to electrolyte imbalance. The rate of death is high prior to diagnosis.
Symptoms
The list of signs and symptoms mentioned in various sources for Bartter's syndrome, antenatal type 1 includes the 37 symptoms listed below: * Premature birth * Polyhydramnios * Severe dehydration following birth * Severe hypercalciuria * Hypokalemic alkalosis * Nephrocalcinosis * Short stature * Mental retardation * Rickets * Weakness * Muscle cramps * Hyperreninism * Hyperaldosteronism * Increased kidney prostaglandin production * Erythrocytosis * Platelet aggregation defect * Impaired vascular responses to angiotensin II * Hypertrophy of juxtaglomerular apparatus * Hyperplasia of juxtaglomerular apparatus * Fetal polyuria * Vomiting * Fever * Diarrhea * Developmental delay if untreated * Failure to thrive if untreated * Prominent forehead * Triangular face * Large eyes * Drooping mouth * Large ears * High urine level of potassium * High urine level of chloride * Loss of potassium from kidneys * Frequent urination * Growth deficiency * Mental retardation * Excessive thirst
Diagnosis
Home medical testing related to Bartter's syndrome, antenatal type 1: * Home Pregnancy Tests * Home Early Pregnancy Tests * Home Ovulation Tests * Home Fertility Tests * Home Rhesus/RH Blood Type Tests * Home Fetal Tests * Fertility-related Home Testing: * Home Ovulation Tests * Home Fertility Tests * Male Fertility Tests * Home Sperm Tests * Sperm Count Tests * Sperm Motility Tests