Acrofacial dysostosis Catania form

Synonyms

3

Overview

One of a group of disorders characterized by defective limb and facial development and the Catania form is very rare.

Symptoms

  • Abnormal dental position
  • Short digits (Finger or Toe)
  • Delayed bone age
  • Downslanted fissures
  • Flat cheek bones
  • Abnormality of the palate (Narrow palate, highly arched palate)
  • Abnormality of the philtrum
  • Brachydactyly syndrome
  • Cognitive impairment
  • Finger syndactyly
  • High forehead
  • Hypoplasia of the zygomatic bone
  • Short and Small nose
  • Short palm
  • Short stature
  • Irregular finger shape
  • Long upper lip groove
  • Low set ears
  • Mental retardation
  • Small head
  • Small jaw
  • Recessed jaw
  • Flat upper lip groove
  • Dwarfism
  • Simian crease
  • Small hand
  • Spina bifida occulta
  • Wooly hair
  • Frizzy hair
  • Infant feeding problems
  • Underdeveloped thumb
  • Abnormally located urethral opening
  • Epispadias
  • Retarded fetal growth
  • Thin eyebrows
  • Low frontal hair line
  • Preauricular pits
  • Undescended testes
  • Ectopic testes
  • Anodontia
  • Oliogodontia
  • Curved fifth finger
  • Coarse hair
  • Thick hair
  • Inguinal hernia
  • Premature birth
  • Webbed neck
  • Facial cleft

Diagnosis

Mandibulofacial dysostosis, Treacher-Collins syndrome. Nager syndrome can be differentiated from Miller syndrome since it is pre and not post axial.

Resources

  • NIH