The PORTRAIT Study

Hypophosphatasia

Prospective, Longitudinal, Observational Registry of Adult Patients With Hypophosphatasia (REG-HYPO) A Prospective Sub-Study of the Global Hypophosphatasia Registry United States Hypophosphatasia Molecular Research Center Study of ALXN1850 in Participants With Hypophosphatasia (HPP) Unraveling Genetics of HypoPhosPhatasia (HPP Genetics) Circulating miRNAs and Bone Microstructure in Adults With Hypophosphatasia The PORTRAIT Study Pharmacokinetic and Dose Response Study of Asfotase Alfa in Adult Patients With Pediatric-Onset Hypophosphatasia (HPP) An Observational, Longitudinal, Prospective, Long-Term Registry Of Patients With Hypophosphatasia (HPP) Burden of Disease in Hypophosphatasia (HPP) Dose Escalation Study to Evaluate the Safety and Tolerability of Multiple Infusions of BPS804 in Adults With Hypophosphatasia (HPP) Evaluation of Bone Architecture and Bone Strength in Adults With Hypophosphatasia (HPP) Relieving Burden of Hypophosphatasia in Adults With Functional Impairment Due to Chronic Disease Patient Reported Outcomes in Adults With Pediatric-onset Hypophosphatasia Treated With Strensiq® (Asfotase Alfa) Safety and Efficacy of Asfotase Alfa in Patients With Hypophosphatasia (HPP) Health Burden of Hypophosphatasia Evaluate and Monitor Physical Performance of Adults Treated With Asfotase Alfa for Hypophosphatasia Characterisation of Adult-Onset Hypophosphatasia