Dose Safety, Tolerability, and Immunogenicity of a New Smallpox Vaccine in Adults Without Previous Smallpox Vaccination

Smallpox

U.S. Army Medical Research and Materiel Command – Smallpox

Safety and Tolerability Study of the VAC∆6 Vaccine in Volunteers Aged 18-40 Years Assessment of Myocarditis After Replication-Deficient Smallpox Immunization Safety, Tolerability and Pharmacokinetics of TPOXX When Administered Orally for 28 Day Study to Assess the Safety and Pharmacokinetics of TPOXX® When Administered Orally for 28 Days Drug-drug Interaction Study of TPOXX When Co-administered With Phosphate Binders Safety, Tolerability and PK of TPOXX in Adults Weighing More Than 120 KG Poly-ICLC to Prevent Respiratory Viral Infections A Safety Study An Open-Label Phase II Study to Evaluate Immunogenicity and Safety of a Single IMVAMUNE Booster Vaccination Two Years After the Last IMVAMUNE Vaccination in Former POX-MVA-005 Vaccinees Tecovirimat (ST-246) Treatment for Orthopox Virus Exposure VHA Clinicians and Bioterror Events: Interactive Web-based Learning Combination Study With MVA BN and Dryvax Dryvax Dilution-Prev Vacc Adults Phase I Trial of an Investigational Small Pox Medication Study on Safety, Tolerability and Immunogenicity of an MVA Vaccine Administered to Healthy Subjects A Trial to Assess the Safety, Tolerability, and Pharmacokinetics of the Anti-Orthopoxvirus Compound Tecovirimat Vaccinia Virus Vaccine (APSV) in Vaccinia- Naive Subjects: PILOT Lyophilized IMVAMUNE® (1×10^8 TCID50) Versus Liquid IMVAMUNE® (1×10^8 TCID50) Administered Subcutaneously and a Lower Dose Liquid IMVAMUNE® (2×10^7 TCID50) Administered Intradermally Safety Surveillance Study of ACAM2000® Vaccinia Vaccine Safety Surveillance Cohort Study of Vaccinia Vaccine (ACAM2000®) ACAM 3000 MVA at Harvard Medical School Post-licensure Department of Defense (DOD) Screening Accuracy Study in Military Personnel Safety and Immunogenicity Study of LC16m8, a Modified Smallpox Vaccine, in Healthy, Previously Unvaccinated Volunteers Safety and Efficacy of CJ-50300 in Healthy Volunteers A Study to Evaluate Safety and Immunogenicity of One and Two Doses of IMVAMUNE® Smallpox Vaccine in 56-80 Year Old Vaccinia-experienced Subjects A Phase II Trial to Compare a Liquid-frozen and a Freeze-dried Formulation of IMVAMUNE (MVA-BN®) Smallpox Vaccine in Vaccinia-naïve Healthy Subjects A Trial to Evaluate Immunogenicity and Safety of Three Consecutive Production Lots of IMVAMUNE® (MVA-BN®) Smallpox Vaccine in Healthy, Vaccinia-naïve Subjects A Randomized, Double-blind, Placebo-controlled Study on Immunogenicity and Safety of MVA-BN (IMVAMUNE™) Smallpox Vaccine in Healthy Subjects Safety and Immunogenicity of CJ-50300 MVA Post-Event: Administration Timing and Boost Study Phase II Trial to Assess Safety and Immunogenicity of IMVAMUNE® Expanded Dryvax Dilution Study in Previously Vaccinated Adults Phase 2 Study of Safety, Tolerability, and Immunogenicity of Three Dose Levels of ACAM3000 Smallpox Vaccine Study of Reactogenicity, Safety, Immunogenicity, and Pock Lesion Formation of a Cell-Cultured Smallpox Vaccine Compared to Dryvax® Evaluation of Take and Safety of a Smallpox Vaccine in Healthy Young Adults Dose Safety, Tolerability, and Immunogenicity of a New Smallpox Vaccine in Adults Without Previous Smallpox Vaccination Take Rate, Immunogenicity and Safety of Elstree-BN Smallpox Vaccine in Healthy Vaccinia-Naive Subjects A Phase 4, Observational Field Study to Evaluate TPOXX in Patients With Smallpox APSV in Vaccinia Naive Adults Human Immune Responses Smallpox A Study of Dryvax Vaccine Against Smallpox in Previously Unvaccinated Adults Freeze-Dried MVA-BN® Lot Consistency Smallpox Trial Dose-finding Study to Evaluate Immunogenicity of Three Different Dose Levels of the IMVAMUNE (MVA-BN) Smallpox Vaccine. Safety, Tolerability, and Immune Response of ACAM3000 Modified Vaccinia Ankara (MVA) Smallpox Vaccine in Adults A Long-Term Study of Healthy Adults Vaccinated With One Dose of Smallpox Vaccine (LISTER Strain) Safety Study of MVA Smallpox Vaccine in HIV-positive Subjects Who Are Vaccinia Naive Dressing Preparations for Smallpox Safety Study of MVA Smallpox Vaccine in Subjects With a History of Atopic Dermatitis (AD) Effect of Dose, Safety, Tolerability of a New Smallpox Vaccine in Adults Without Previous Smallpox Vaccination Safety and Efficacy of CJ Smallpox Vaccine in Previously Vaccinated Healthy Volunteers Dose Study of ACAM2000 Smallpox Vaccine in Previously Vaccinated Adults Safety and Efficacy of CJ Smallpox Vaccine in Healthy Volunteers Randomized, Open-label Phase II Trial to Assess the Safety and Immunogenicity of MVA-BN Smallpox Vaccine in Immunocompromised Subjects With HIV Infection