Bone Marrow Transplantation in Young Adults With Severe Sickle Cell Disease
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Invasive Infections in Children With Hemoglobinopathies
Intranasal Fentanyl Versus Intravenous Morphine in the Treatment of Severe Painful Sickle Cell Crises in Children
A Comprehensive Care Plan for Pediatric Patients With Vaso-Occlusive Crises
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A Pilot Study of HSCT for Patients With High-risk Hemoglobinopathy Using a Nonmyeloablative Preparative Regimen
Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies
Longterm Follow-up of Subjects With Hemoglobinopathies Treated With Ex Vivo Gene Therapy
Use of Mobile Technology for Intensive Training in Medication Management
Preventing Acute Chest Syndrome by Transfusion Feasibility Study
Angiotensin-converting Enzyme Inhibitors and Early Sickle Cell Renal Disease in Children
Cerebrovascular Reserve and White Matter Disease in Patients With Chronic Anemia
Hydroxyurea Management in Kids: Intensive Versus Stable Dosage Strategies
Stem Cell Transplantation After Reduced-Dose Chemotherapy for Patients With Sickle Cell Disease or Thalassemia
Silent Cerebral Infarct Transfusion Multi-Center Clinical Trial
Nitric Oxide and Sickle Cell Pain
Near Infrared Spectroscopy in Sickle Cell Pediatric Patients
Is the Preoperative Preparation of Sickle Cell Patients Optimal: Assessment of Practices and Post-operative Complications
Inhaled Mometasone to Promote Reduction in Vasoocclusive Events 2
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Losartan for Sickle Cell Kidney Disease
sPLA2 in EBC During Acute Chest Syndrome
Re-Aiming at Hydroxyurea Adherence for Sickle Cell With mHealth
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A Phase I/II Trial of Recombinant-Methionyl Human Stem Cell Factor (SCF) in Adult Patients With Sickling Disorders
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Early Diagnosis of Sickle Acute Chest Syndrome Using a Combination of Plasma Bimarkers and Chest Imaging
Home Based Massage and Relaxation for Sickle Cell Pain
Treatment of Sickle Cell Patients Hospitalized in Pain Crisis With Prophylactic Dose Low-molecular-weight Heparin (LMWH) Versus Placebo
Adjuvant Low-dose Ketamine in Pediatric Sickle Cell Vaso-occlusive Crisis
Optimizing Hydroxyurea Therapy in Children With SCA In Malaria Endemic Areas
Novel Dose Escalation to Predict Treatment With Hydroxyurea
EXTEND EXpanding Treatment for Existing Neurological Disease
HSCT For Patients With High Risk Hemoglobinopathies Using Reduced Intensity
Regional Anesthesia for Sickle Cell Crisis Using Ultrasound in The Emergency Department: Phase I
Phase II Randomized Trial:Arginine Butyrate Plus Standard Local Therapy in Patients With Refractory Sickle Cell Ulcers
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Gaming Technology to Engage Adolescent Sickle Cell Patients in Pain Management
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Phosphodiesterase Type-5 Inhibitor Therapy in Sickle Cell People With Pulmonary Hypertension
Methadone in Pediatric and Adult Sickle Cell Patients
Transillumination Device for Peripheral Intravenous Placement in Patients With Sickle Cell Disease (PERFID)
Hydroxyurea and Magnesium Pidolate to Treat People With Hemoglobin Sickle Cell Disease
Hydroxyurea Optimization Through Precision Study
Realizing Effectiveness Across Continents With Hydroxyurea (REACH)
Evaluation of Non-invasive Endothelial Function in Children Sickle by Vascular Ultrasound
Inhaled Nitric Oxide for Pediatric Painful Sickle Crisis
TAPS2 Transfusion Antenatally in Pregnant Women With SCD
Ketamine for Acute Painful Crisis in Sickle Cell Disease Patients
Dissemination and Implementation of Stroke Prevention Looking at the Care Environment
THE IMPROVE TRIAL: Improving Pain Management and Outcomes With Various Strategies of Patient-Controlled Analgesia (PCA)
Pulmonary Hypertension, Hypoxia and Sickle Cell Disease
Cognitive Behavioral Therapy and Real-time Self-management Intervention for SCD Via Mobile Applications
Collection of Human Biospecimens for Basic and Clinical Research Into Alpha Globin Variants
Multicenter Observational Study on Myocardial Iron Overload in 3 Multitransfused Populations
Dense Red Blood Cells in Sickle Cell Children
Phase 2 Study of MP4CO to Treat Vaso-occlusive Sickle Crisis
Sickle Cell Anemia Screening and Prevention in Northern Israel
Carbon Monoxide Monitor for the Measurement of End-Tidal Carbon Monoxide Levels in Children With or Without Hemolysis
Ameliorating Attention Problems in Children With Sickle Cell Disease (SCD)
Bone Marrow Transplantation, Hemoglobinopathies, SCALLOP
Evaluation of Sickle Cell Liver Disease
Stigma, Self-management, & Quality of Life in SCD
Combined Use of a Respiratory Broad Panel Multiplex PCR and Procalcitonin to Reduce Antibiotics Exposure in Hospitalized Sickle-cell Adults With Acute Chest Syndrome.
Blood Collection for Research Related to Certain Diseases Involving Blood Vessels
Intravenous Gammaglobulin for Sickle Cell Pain Crises
Allogeneic Bone Marrow Transplantation for the Treatment of Genetic Disorders of Erythropoiesis
Evaluation of the Impact of Renal Function on the Pharmacokinetics of SIKLOS ® (DARH)
HRV-B for Symptom Management in Sickle Cell Patients
Sickle Cell Pain: Intervention With Capsaicin Exposure
Comparison of Patient Controlled Analgesia (PCA) Versus Bolus Narcotic Therapy for the Treatment of Vaso-Occlusive Crisis (VOC)
Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias
Pharmacokinetics and Pharmacodynamics Study of SEG101 (Crizanlizumab) in Sickle Cell Disease (SCD) Patients With Vaso- Occlusive Crisis (VOC)
FOCUS for Pediatric Sickle Cell Disease and Cancer
SIKAMIC (SIklos on Kidney Function and AlbuMInuria Clinical Trial)
Long Term Follow up in Sickle Cell Patients Treated by Hydroxyurea
Sickle Cell Hemoglobinopathies and Bone Health
Validation of the Sickle Cell Disease Pain Burden Interview
Motivations, Expectations, and Decision-making of Sickle Cell Patients in Clinical Research
A Phase 1 Study of Continuous Intravenous L-citrulline During Sickle Cell Pain Crisis or Acute Chest Syndrome
Topical Sodium Nitrite for Chronic Leg Ulcers in Adult Patients With Blood Disorders
Pediatric Hydroxyurea Phase III Clinical Trial (BABY HUG) Follow-up Observational Study II Protocol
Primary Prevention of Stroke in Children With SCD in Sub-Saharan Africa II
RHD Genotype Matching for Anti-D
Monocytic Expression of Heme Oxidase-1 (HO-1) in Sickle Cell Patients and Correlation With the Humoral Immune Response to Vaccine and With Allo-immunization.
Albuminuria Reduction With Renin Angiotensin System Inhibitors in SCA Patients
Substudy of CADRE: for People With Extreme Phenotype: BIOCADRE
RH Genotype Matched RBC Transfusions
A Phase – IIa – IIb, Trial to Study the Safety, Tolerability and Efficacy of Memantine as a Long-term Treatment of SCD
Early Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell Transplantation
Sevuparin Infusion for the Management of Acute VOC in Subjects With SCD
Evaluation of the AMICUS RBCx System in Sickle Cell Patients
Losartan to Reverse Sickle Nephropathy
Evaluation of Repeat Administration of Purified Poloxamer 188
Prevention of Vaso-occlusive Painful Crisis by Using Omega-3 Fatty Acid Supplements
Age of Blood in Sickle Cell Transfusion
Effectiveness of New Analgesic Strategy Compared to the Usal Antalgic Strategy
Self-Management for Youth and Families Living With SCD – SMYLS
Rejuvesol® Washed RBC in Sickle Cell Patients Requiring Frequent Transfusions
Hydroxyurea and Transfusion
Study to Assess the Effect of Long-term Treatment With GBT440 in Participants Who Have Completed Treatment in Study GBT440-031
Sub-dissociative Intranasal Ketamine for Pediatric Sickle Cell Pain Crises
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Hydroxyurea Adherence for Personal Best in Sickle Cell Treatment: HABIT
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Quality of Care of Children With Sickle Cell Disease (SCD) Screened at Birth in France
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Evaluation of the Safety, Tolerability, Pharmacokinetics (PK) and Effects on Liver Iron Concentration of ICL670 Relative to Deferoxamine(DFO).
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Haploidentical PBMC Transplant for Severe Congenital Anemias
Transcranial Doppler (TCD) With Transfusions Changing to Hydroxyurea
Moderate Dose Hydroxyurea for Secondary Stroke Prevention in Children With Sickle Cell Disease in Sub-Saharan Africa
Role of Virtual Reality (VR) in Patients With Sickle Cell Disease (SCD)
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Neutrophil Extracellular Traps and Sickle Cell Disease
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Vitamin D for Sickle Cell
High-flow Oxygen for Vaso-occlusive Pain Crisis
Intermittent Preventive Treatment for Malaria in Patient With Sickle Cell Disease
Rifaximin to Modify the Disease Course in Sickle Cell Disease
New Hemolysis Parameters in Sickle Cell Disease
Phase III Randomized Study of Poloxamer 188 for Vaso-Occlusive Crisis of Sickle Cell Disease
Assessment of Opioid Analgesia in Sickle Cell
Topical Sodium Nitrite in Sickle Cell Disease and Leg Ulcers
Sparing Conversion to Abnormal TCD (Transcranial Doppler) Elevation (SCATE)
Sickle Cell Clinical Research and Intervention Program
Long Term Effects of Erythrocyte Lysis
Parent Willingness to Participate in Tobacco Trials in the Pediatric Clinical Setting
Study of Clotrimazole and Hydroxyurea in Patients With Sickle Cell Syndromes
Blood Flow and Pain Crises in People With Sickle Cell Disease
Shared-Decision Making for Hydroxyurea
Inhaled Mometasone to Reduce Painful Episodes in Patients With Sickle Cell Disease
A Study Evaluating the Safety and Efficacy of the LentiGlobin BB305 Drug Product in Severe Sickle Cell Disease
Apixaban in Patients With Sickle Cell Disease
Non-Myeloablative Conditioning and Bone Marrow Transplantation
An Extension Study to Further Evaluate the Safety, Tolerability of GBT440 in Patients With Sickle Cell Disease Who Participated in the Study GBT440-001
Parent Educational Program for Children With Sickle Cell Disease
Acute Kidney Injury in Patients With Sickle Cell Disease
Music Therapy in Sickle Cell Pain Mixed Methods Study
Improving Parental Psychosocial Functioning and Early Developmental Outcomes in Children With Sickle Cell Disease
Phase I/II Randomized Study of Hydroxyurea With or Without Clotrimazole in Patients With Sickle Cell Anemia
Curative Versus Disease-Modifying Therapies in Children With Severe Sickle Cell Disease
To Assess Safety, Tolerability and Physiological Effects on Structure and Function of AXA4010 in Subjects With Sickle Cell Disease
Expanded Access to Voxelotor for Patients With Sickle Cell Disease Who Have No Alternative Treatment Options
Safety Of Rivipansel (GMI-1070) In The Treatment Of One or More Vaso-occlusive Crises In Hospitalized Subjects With Sickle Cell Disease
BEATS 2: Music Therapy in Sickle Cell
Abatacept for GVHD Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease
Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor
A Safety and Efficacy Study Evaluating CTX001 in Subjects With Severe Sickle Cell Disease
Sleep Study in Adult Patients With Major Sickle Cell Disease With Paroxysmal Nocturnal Events
Hemoglobin Desaturation in Sickle Cell Disease
Evaluation of Spectra Optia Red Blood Cell Exchange in Sickle Cell Patients
Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure
Effects of HQK-1001 in Patients With Sickle Cell Disease
Patient-Provider Tools to Improve the Transition to Adult Care in Sickle Cell Disease
A Study of HQK-1001 in Patients With Sickle Cell Disease
Study of Propranolol as Anti-Adhesive Therapy in Sickle Cell Disease (SCD)
Heart Arteries and Sickle Cell Disease / Coeur Artères DREpanocytose
Epidemiology of Silent and Overt Strokes in Sickle Cell Disease
Microvascular and Cardiac Dysfunction in Paroxysmal Nocturnal Hemoglobinuria and Sickle Cell Disease
Assessing the Safety of Buprenorphine in People With Sickle Cell Disease
Pediatric Open-Label Extension of Voxelotor
Pulmonary Hypertension in Patients With Sickle Cell Disease in Nigeria
Integration of mHEALTH Into the Care of Patients With Sickle Cell Disease to Increase Hydroxyurea Utilization
Iron Overload Assesment in Sickle Cell Anemia and Sickle Cell Thalassemia
Steroid Treatment for Sickle Cell Pain Crisis
Epidemiology and Pathophysiological Mechanisms of HTAP in SS and SC Children in Martinique and Guadeloupe.
Dose Escalation Study to Evaluate the Safety, Tolerability, PK and PD of Voxelotor in Patients With SCD
Computerized Cognitive Behavioral Therapy Assisted Life Management for Pain in Sickle Cell Disease
Single-center Prospective Evaluation of Sickle Cell Patient Care in the CHU Brugmann Emergency Department
Long-term Safety and Efficacy of Ferriprox® in Iron Overloaded Patients With Sickle Cell Disease or Other Anemias
Intranasal Ketamine For Pain Control In Patients With Sickle Cell Disease And Vaso-occlusive Episode (VOE) In The PED
Tricuspid Regurgitant Jet Velocity as an Independent Marker for Mortality in Sickle Cell Anemia
A Blood Stem Cell Transplant for Sickle Cell Disease
Central Nervous System Vascular Changes in Adult Sickle Cell Disease and the Effect of Treatment With Simvastatin
Efficacy and Safety of Ferriprox® in Patients With Sickle Cell Disease or Other Anemias
Evaluation of Knowledge Among Adolescents With Sickle Cell Disease.
Management of Severe Acute Malnutrition in SCD, in Northern Nigeria
Improving Sickle Cell Disease (SCD) Care Using Web-based Guidelines
A Study of Patients Having Pulmonary Hypertension Associated With Sickle Cell Disease and Completing an ASSET Study
Implication of the Oxydative Stress in the Pathophysiology of Sickle Cell Anemia:
SCD-Haplo: Phase II Study of HLA-Haploidentical SCT for Aggressive SCD
A Study of the Safety, Blood Levels and Biological Effects of GBT440 in Healthy Subjects and Subjects With Sickle Cell Disease
Study of Methodologies to Measure Blood Flow and Oxygenation in Adults With Sickle Cell Disease
Nitric Oxide Therapy for Acute Chest Syndrome in Sickle Cell Disease Children
Arginine Therapy for Sickle Cell Disease Pain
A SAD/MAD to Assess the Safety, Pharmacokinetics and Pharmacodynamics of FT-4202 in Healthy Volunteers and Sickle Cell Disease Patients
Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease
Effectiveness of a Computerized Tool (PAINRelieveIt) to Help Manage Pain Related to Sickle Cell Disease
A Stratified Sickle Event Randomized Trial (ASSERT)
Decompression Coring Versus Conservative Therapy in Patients With Avascular Necrosis of the Hip Related to Sickle Cell Disease
T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias
Hydroxyurea and Erythropoietin to Treat Sickle Cell Anemia
Functional Neuroimaging of Pain Using EEG and fMRI
Study of Deferasirox Relative to Subcutaneous Deferoxamine in Sickle Cell Disease Patients
Autologous Bone Marrow Stem Cell Transplantation for Osteonecrosis in Sickle Cell Disease
ElectroNic Hydroxyurea AdhereNCE: A Strategy to Improve Hydroxyurea Adherence in Patients With Sickle Cell Disease
Comparison of Allogeneic Matched Related Haematopoietic Stem Cell Transplantation After a Reduced Intensity Conditioning Regimen With Standard of Care in Adolescents and Adults With Severe Sickle Cell Disease
An Extension Study of IMR-687 in Adult Patients With Sickle Cell Anemia
Screening Patients With Sickle Cell Disease for Kidney Damage
Defibrotide in Sickle Cell Disease-Related Acute Chest Syndrome
Androgen Regulation of Priapism in Sickle Cell Disease
A Study of the Effect of IW-1701 (Olinciguat), a Stimulator of Soluble Guanylate Cyclase (sGC), on Patients With Sickle Cell Disease (SCD)
Adherence to Hydroxyurea in Children With Sickle Cell Anemia
iCanCope With Sickle Cell Pain
Sickle Cell Anemia and Cerebral Microcirculation : Multimodal Exploration
Transfusion in Sickle Cell Disease: Screening of Sickle Cell Disease Trait in Blood Donors
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Escalating Multiple Oral Doses of AG-348 in Subjects With Stable Sickle Cell Disease
A Single Dose Study of the Safety, Blood Levels and Biological Effects of Aes-103 Compared to Placebo in Subjects With Stable Sickle Cell Disease
Mesenchymal Stromal Cells for Haplo Hematopoietic Cell Transplantation for Sickle Cell Disease
Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell Disease
Using Patient-Centered Guidelines in a Technology Platform to Improve Health Care in Adults With Sickle Cell Disease
Evaluation of a Training Program for Homozygous Sickle Cell Disease Patients
Effect of Exercise With and Without HMB on Body Composition and Muscle Strength in Sickle Cell Anaemia
Safety and Efficacy of Gene Therapy of the Sickle Cell Disease by Transplantation of an Autologous CD34+ Enriched Cell Fraction That Contains CD34+ Cells Transduced ex Vivo With the GLOBE1 Lentiviral Vector Expressing the βAS3 Globin Gene in Patients With Sickle Cell Disease (DREPAGLOBE)
Impact on the Length of Stay in Incentive Spirometry and Pain in the Decompensation of Sickle Cell Disease: .
Muscle Function and Its Biological and Physiological Determinants in Sickle Cell Disease
Safety of Single Ascending Doses of CSL889 in Adult Patients With Stable Sickle Cell Disease
Sickle Cell Disease and CardiovAscular Risk – Red Cell Exchange Trial (SCD-CARRE)
Dose-Finding Study of SC411 in Children With Sickle Cell Disease
A Pilot Study on Neuroimaging in SCD: Part of The Boston Consortium to Cure Sickle Cell Disease
Low-Dose Ketamine Infusion for Children With Sickle Cell Disease-Related Pain
The Brigance Assessment Of Individual Neurodevelopment In Young Children With Sickle Cell Disease- 2
Comparing Individualized vs. Weight Based Protocols to Treat VOE in SCD Occlusive Episodes in Sickle Cell Disease
Cognitive Rehabilitation in Sickle Cell Disease
The Effect of Rivaroxaban in Sickle Cell Disease
Sulfadoxine- Pyrimethamine Versus Weekly Chloroquine for Malaria Prevention in Children With Sickle Cell Anemia
Decision Aid for Therapeutic Options In Sickle Cell Disease
Pathophysiology of Acute Pain in Patients With Sickle Cell Disease
Implications of a Paediatrician-psychologist Tandem for Sickle Cell Disease Care and Impact on Cognitive Functioning
Vascular Function Intervention Trial in Sickle Cell Disease
A Study Evaluating Gene Therapy With BB305 Lentiviral Vector in Sickle Cell Disease
Decitabine for High-Risk Sickle Cell Disease
Acceptability, Feasibility and Safety of a Yoga Program for Chronic Pain in Sickle Cell Disease
Vaporized Cannabis for Chronic Pain Associated With Sickle Cell Disease
Effectiveness of Laying-on-of-hands for Sickle Cell Disease
Improving Self-Management in Adolescents With Sickle Cell Disease
Adenosine 2A Agonist Lexiscan in Children and Adults With Sickle Cell Disease
Trial of Zileuton CR in Children and Adults With Sickle Cell Disease
Efficacy of Vorinostat to Induce Fetal Hemoglobin in Sickle Cell Disease
Transfusion in Sickle Cell Disease: Risk Factors for Alloimmunization
Phase 1/2 Study to Evaluate the Safety, Tolerability and Pharmacokinetics of HQK-1001 Administered Daily in Patients With Sickle Cell Disease
Glucose Metabolism in Sickle Cell Disease
Sildenafil Therapy for Pulmonary Hypertension and Sickle Cell Disease
Improving Disease Knowledge in Adolescents With Sickle Cell Disease
Sickle Cell Anemia – A Comparative Study Between Three Ethnical Communities, a Multicenter Study
Effect of Atorvastatin on Endothelial Dysfunction and Albuminuria in Sickle Cell Disease
Haploidentical Hematopoietic Stem Cell Transplantation (HSCT) for Patients With Severe Sickle Cell Disease
Feasibility of a Stress Reduction Intervention Study in Sickle Cell Disease
Ketamine as an Adjuvant Therapy for Acute Vaso Occlusive Crisis in Pediatric Patients With Sickle Cell Disease
Collect of Cord Blood From Subjects at Risk for Sickle Cell Disease, for the Purpose of Laboratory Research
Escalation of Plerixafor for Mobilization of CD34+ Hematopoietic Progenitor Cells and Evaluation of Globin Gene Transfer in Patients With Sickle Cell Disease
Pilot Study on the Effects of Intravenous Ketamine on Acute Pain Crisis in Patients With Sickle Cell Disease
Effects of Nitric Oxide and Nitroglycerin in Patients With Sickle Cell Anemia
Patient Centered Comprehensive Medication Adherence Management System in Patients With Sickle Cell Disease
Gene Transfer for Sickle Cell Disease
Risk-based Therapy for Sickle Cell Anemia: A Feasibility Study
Study to Evaluate the Effect of Voxelotor Administered Orally to Patients With Sickle Cell Disease (GBT_HOPE)
SACRED A Prospective Research Study to Reduce Stroke in Children With Sickle Cell Anemia
A Study to Assess the Safety, Tolerability, and Efficacy of BIVV003 for Autologous Hematopoietic Stem Cell Transplantation in Patients With Severe Sickle Cell Disease
Nonmyeloablative Conditioning for Mismatched Hematopoietic Stem Cell Transplantation for Severe Sickle Cell Disease
Heart Disease in Sickle Cell Anemia
Study of Decitabine and Tetrahydrouridine (THU) in Patients With Sickle Cell Disease
A Reduced Toxicity Allogeneic Unrelated Donor Stem Cell Transplantation (SCT) for Severe Sickle Cell Disease
Study Exploring the Effect of Crizanlizumab on Kidney Function in Patients With Chronic Kidney Disease Caused by Sickle Cell Disease
A Pilot Study of Fecal Microbiome and Neutrophil Cellular Adhesion Molecules in Patients With Sickle Cell Disease (SCD)
A Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease
A Study of SHP655 (rADAMTS13) in Sickle Cell Disease
A Phase Ib Study of NVX-508 in Sickle Cell Disease
Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease
Macitentan in Pulmonary Hypertension of Sickle Cell Disease
Exhaled Carbon Monoxide as a Marker of Hemolysis in Sickle Cell Disease- an Exploratory Study
Hydroxyurea to Prevent Brain Injury in Sickle Cell Disease
TRF-1101 Assessment in Sickle Cell Disease
Study of Dose Confirmation and Safety of Crizanlizumab in Pediatric Sickle Cell Disease Patients
The Spleen in Sickle Cell Anemia and Sickle Cell Thalassemia
Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myeloid Chimerism Levels
Immunogenicity Study of an Anti-pneumococcal Vaccination Strategy in Patients With Sickle Cells Disease
The Implementation of the Automated Erythrocytapheresis in Egyptian Sickle Cell Disease Center
Acupuncture for Pain in Sickle Cell Disease
Hepcidin Levels in Sickle Cell Disease (SCD)
A Study of IMR-687 in Adult Patients With Sickle Cell Anaemia (Homozygous HbSS or Sickle-β0 Thalassemia)
European Sickle Cell Disease Cohort – Hydroxyurea
Predictors and Outcomes in Patients With Sickle Cell Disease
Study to Assess Safety and Impact of SelG1 With or Without Hydroxyurea Therapy in Sickle Cell Disease Patients With Pain Crises
SMYLS: A Self-management Program for Youth Living With Sickle Cell Disease
Gum Arabic as Fetal Hemoglobin Agent in Sickle Cell Anemia
Pharmacokinetics (PK) of Liquid Hydroxyurea in Pediatric Patients With Sickle Cell Anemia
Pain Management in Children and Young Adults With Sickle Cell Disease
Clinical Trial to Study the Safety and Tolerability of Memantin Mepha® in Sickle Cell Disease Patients
Assessing Function in Pediatric Patients With Sickle Cell Disease
iPeer2Peer Program for Youth With Sickle Cell Disease
Imatinib for Pain in Sickle Cell Anemia
Sildenafil for Treatment of Priapism in Men With Sickle Cell Anemia
L-Glutamine Therapy for Sickle Cell Anemia
Dronabinol for Pain and Inflammation in Adults Living With Sickle Cell Disease
Nitric Oxide and Transfusion Therapy for Sickle Cell Patients With Pulmonary Hypertension
L-Glutamine Therapy for Sickle Cell Anemia and Sickle ß0 Thalassemia
Zinc for Infection Prevention in Sickle Cell Anemia (ZIPS)
Web-MAP Intervention for Youth With Sickle Cell Disease
Study to Evaluate the Effect of GBT440 in Pediatrics With Sickle Cell Disease
Effect of MitoQ on Platelet Function and Reactive Oxygen Species Generation in Patients With Sickle Cell Anemia
Stem Cell Transplantation for Sickle Cell Anemia
Zinc Supplementation in Children With Sickle Cell Disease in Western Kenya
The Feasibility of the PAINReportIt Guided Relaxation Intervention-Outpatient
Effect of Ticagrelor vs. Placebo in the Reduction of Vaso-occlusive Crises in Pediatric Patients With Sickle Cell Disease
Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients
Carbon Monoxide Levels and Sickle Cell Disease Severity
Myeloablative Conditioning, Prophylactic Defibrotide and Haplo AlloSCT for Patients With Sickle Cell Disease
Ibuprofen and Opioid (Morphine or Diamorphine) for Acute Pain in Sickle Cell Disease – Sickle With Ibuprofen & Morphine
Peripheral Blood Stem Cell Collection for Sickle Cell Disease (SCD) Patients
Treatment of Sickle Cell Anemia With Stem Cell Transplant
Neurovascular Determinants of Cognitive Function in Adults With Sickle Cell Disease
Atorvastatin Therapy to Improve Endothelial Function in Sickle Cell Disease
Stem Cell Transplant in Patients With Severe Sickle Cell Disease
Study of Blood Platelets in Sickle Cell Disease
Clinical and Laboratory Characteristics of Sickle Cell Anemia Patients Admitted With Fever
Endothelial Function in Patients With Sickle Cell Anemia Before and After Sildenafil
Evaluating Barriers to Stroke Screening and Prevention in Children With Sickle Cell Disease
Codeine in Sickle Cell Disease
Autologous Bone Marrow Stem Cells for Chronic Leg Ulcer Treatment in Sickle Cell Disease
Safety of Blood Stem Cell Mobilization With Plerixafor in Patients With Sickle Cell Disease
Tadalafil for Treatment of Priapism in Men With Sickle Cell Anemia
N-Acetylcysteine in Patients With Sickle Cell Disease
Analysis of T-Cell Immune Reconstitution Following Allogeneic Hematopoietic BMT for Severe SCD
Hydroxyurea Adherence for Personal Best in Sickle Cell Disease (HABIT): Efficacy Trial
A Study of the Efficacy and Safety of ICA-17043 (With or Without Hydroxyurea) in Patients With Sickle Cell Anemia.
Inhaled Corticosteroid Use to Prevent Acute Chest Syndrome Recurrence in Children Between 1 and 4 With Sickle Cell Disease: a Feasibility Trial
Absorption, Metabolism, and Excretion of a Single Dose of Ferriprox® in Patients With Sickle Cell Disease
A Safety Study of Eptifibatide in Patients With Sickle Cell Disease
A Study Evaluating the Efficacy and Safety of LentiGlobin BB305 Drug Product in Beta-Thalassemia Major and Sickle Cell Disease
Laboratory-based Hypnosis Intervention on Pain Responsivity in Adolescents With Sickle Cell Disease
The Link Between Anemia and Deficits in Memory and Attention in Individuals With Sickle Cell Disease
The Feasibility of the PAINReportIt Guided Relaxation Intervention-INPATIENT
Safety and Efficacy of Sodium Nitrite in Sickle Cell Disease
The Efficacy of Jobelyn (Sorghum Bicolor Extract)in the Treatment of Sickle Cell Anemia
A Rehabilitation Program in Children With Sickle Cell Disease and Cognitive Deficits: a Pilot Study
Cerebrovascular Reserve Measurements in Sickle Cell Disease
Examining the Knowledge, Attitudes, and Beliefs of Sickle Cell Disease Patients, Parents of Patients With Sickle Cell Disease, and Providers Towards the Integration of CRISPR in Clinical Care
A New Reagent Assay Examining Natural Parvovirus B19 Infection in Sickle Cell Disease
MAP to Provide Access to Crizanlizumab, for Sickle Cell Disease Patients
A Pilot Study of Azithromycin Prophylaxis for Acute Chest Syndrome in Sickle Cell Disease
Efficacy, Safety Study and Benefit of Alkali Therapy in Sickle Cell Disease
Nitric Oxide to Improve Blood Flow in Sickle Cell Disease
Risk Clinical Stratification of Sickle Cell Disease in Nigeria, Assessment of Efficacy/Safety of Hydroxyurea Treatment
A Multi-Center Study of Riociguat in Patients With Sickle Cell Diseases
Sickle Cell Disease Conditioning for Bone Marrow Transplant
Study of Beet Juice for Patients With Sickle Cell Anemia
Hydroxyurea for the Treatment of Patients With Sickle Cell Anemia
Hematopoietic Stem Cell Transplant for Sickle Cell Disease
Bone Marrow Transplantation vs Standard of Care in Patients With Severe Sickle Cell Disease (BMT CTN 1503)
Music Therapy in Sickle Cell Transition Study
Evaluation of Hydroxyurea Plus L-arginine or Sildenafil to Treat Sickle Cell Anemia
A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease (SCD)
Sickle Cell Disease: A Retrospective Chart Review
Kidney Function in Sickle Cell Anemia
Vitamin D and Bisphosphonates in the Treatment of Sickle Cell Disease
Hypnosis to Manage Pain and Symptoms in Patients With Sickle Cell Disease
Exercise-induced Pulmonary Hypertension in Patients With Sickle-cell Anemia
Kidney Transplantation in Patients With Sickle Cell Disease
Simvastatin (Zocor) Therapy in Sickle Cell Disease
MUSic Therapy to Improve Quality Of Life in Sickle Cell Disease (MUSIQOLS)
Hydroxyurea for Children and Young Adults With Sickle Cell Disease and Pulmonary Hypertension
Omega-3 Fatty Acids in Sickle Cell Disease
Quantifying the Presence of Lung Disease and Pulmonary Hypertension in Children With Sickle Cell Disease
Comparing Acute Pain Management Protocols for Patients With Sickle Cell Disease
Sickle Cell Disease and Endothelial Progenitor Cells (EPCs)
Acupuncture for Adults With Sickle Cell Disease (SCD): A Feasibility Study
Study to Evaluate the Effect of Ticagrelor Versus Placebo in Reducing Vaso-Occlusive Crises Rate in Pediatric Patients With Sickle Cell Disease.
HLA Haploidentical Bone Marrow Transplant in Patients With Severe Sickle Cell Disease
Bone Marrow Transplantation in Treating Children With Sickle Cell Disease
Stem Cell Transplant in Sickle Cell Disease and Thalassemia
Evaluation of Different Dose Regimens of Aes-103 Given for 28 Days to Subjects With Stable Sickle Cell Disease
Pain Management Protocol for Pediatric Sickle Cell Disease
Clinical and Laboratory Assessment of Iron Overload in Sickle Cell Anemia and Sickle Cell Thalassemia
Haploidentical Transplantation With Pre-Transplant Immunosuppressive Therapy for Patients With Sickle Cell Disease
A Study of Varespladib Infusion in Subjects With Sickle Cell Disease.
Sleep Apnea in Sickle Cell Disease
Microvessels and Heart Problems in Sickle Cell Disease
Dose-Escalation Study of SCD-101 in Sickle Cell Disease
Minimizing Toxicity in HLA-identical Related Donor Transplantation for Children With Sickle Cell Disease
Oxygen Therapy and Pregnancy in Sickle Cell Disease
A Study to Evaluate Safety, Pharmacokinetic, and Biological Activity of INCB059872 in Subjects With Sickle Cell Disease
Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease
A Pilot Study of Chronic Red Blood Cell Transfusion in Sickle Cell Disease-Associated Pulmonary Hypertension
Vitamin D Supplementation in Children With Sickle Cell Disease
L-Arginine and Sickle Cell Disease
Aspirin Prophylaxis in Sickle Cell Disease
Sickle Cell Disease: Targeting Alloantibody Formation Reduction; Risk Factors, and Genetics
Novel Cardiac Magnetic Resonance Imaging to Define a Unique Restrictive Cardiomyopathy in Sickle Cell Disease
DREPAMASSE Study – Evaluation of a Newborn Screening for Sickle Cell Disease by Tandem Mass Spectrometry
Study of Hydroxyurea to Treat Sickle Cell Disease
Evaluation of the Prevalence of Pulmonary Hypertension in Adult Patients With Sickle Cell Disease
A Phase III Safety and Efficacy Study of L-Glutamine to Treat Sickle Cell Disease or Sickle βo-thalassemia
A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease
A Phase II Trial of Regadenoson in Sickle Cell Anemia
Establishment of Functional MRI Imaging Parameters for Use in the Evaluation of Sickle Cell Disease
Study of a Red Blood Cell Deformability Parameter in Patients With Sickle Cell Disease
Sickle Cell Disease Biofluid Chip Technology (SCD BioChip)
Sleep Respiratory Disorders Evaluation in Sickle Cell Disease Children
SMART Mobile Application Technology Utilization in the Treatment of Sickle Cell Disease Post Day Hospital Discharge
The Role of Endothelin-1 in Sickle Cell Disease
Adolescent, Caregiver, and Young Adult Perspectives of the Transition From Pediatric to Adult Care for Sickle Cell Disease: A Preliminary Evaluation of the Sickle Cell Disease Transition Program
Long Term Effects of Hydroxyurea Therapy in Children With Sickle Cell Disease
Neuropathic Pain in Jamaicans With Sickle Cell Disease
Families Taking Control (FTC): Family-based Problem-solving Intervention for Children With Sickle Cell Disease
Measurement of Cerebral Blood Flow Using Transcranial Doppler Ultrasound in Children With Sickle Cell Disease
Efficacy of a Decision Aid for Hydroxyurea in Sickle Cell Disease
Sickle Cell Disease, Hemechip
Transplantation Using Reduced Intensity Approach for Patients With Sickle Cell Disease From Mismatched Family Donors of Bone Marrow
Medication Adherence in Youth With Sickle Cell Disease (SCD)
The Feasibility of Text Messaging to Assess Secondhand Smoke Exposure Among Youngsters With Cancer or Sickle Cell Disease
Study of Efficacy, Safety and Tolerability of ACZ885 (Canakinumab) in Pediatric and Young Adult Patients With Sickle Cell Anemia
A Randomized Trial of LOVAZA in Pediatric Sickle Cell Disease (SCD)
Stem Cell Transplantation With Identical Donors for Patients With Sickle Cell Disease
Study to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell Disease
A Sickle CEll Disease ComplicatioN Trial
Hydroxyurea in Young Children With Sickle Cell Anemia
Contraception in Women With Sickle Cell Disease
Study of Panobinostat (LBH589) in Patients With Sickle Cell Disease
Study of SANGUINATE™ Versus Hydroxyurea in Sickle Cell Disease (SCD) Patients
Effect of Simvastatin Treatment on Vaso-occlusive Pain in Sickle Cell Disease
Inflammatory Response to Hydroxyurea Therapy in Sickle Cell Disease
Blood Sampling for Research Related to Sickle Cell Disease
Pediatric -Adult Care Transition Program of Patients With Sickle Cell Disease
Assessment of Algorithm-Based Hydroxyurea Dosing on Fetal Hemoglobin Response, Acute Complications, and Organ Function in People With Sickle Cell Disease
Qualitative Survey of Potential Exercise Activity in Adults With Sickle Cell Anemia (SCA)
Sickle Cell Anemia in an Arab Bedouin Village in the Northern Israel
Non-Myeloablative Bone Marrow Transplant for Patients With Sickle Cell Anemia and Other Blood Disorders
Hydroxyurea in the Treatment of Sickle Cell Disease
Ph I/II Study of Allogeneic SCT for Clinically Aggressive Sickle Cell Disease (SCD)
Working Memory and School Readiness in Preschool-Aged Children With Sickle Cell Disease
MACS Study – Microparticles and Coagulation in Sickle Cell Disease
Stem Cell Gene Therapy for Sickle Cell Disease
Safety, Pharmacokinetic, and Pharmacodynamic Study of NKTT120 in Adult Patients With Stable Sickle Cell Disease (SCD)
A Phase 2 Study of the Effects of 6R-BH4 in Subjects With Sickle Cell Disease
State Of The Art Functional Imaging In Sickle Cell Disease
Study of Intravenous GMI-1070 in Adults With Sickle Cell Disease
Survey in a Population of Sickle Cell Disease Patients to Evaluate the Transition Between the Queen Fabiola Children Hospital and the CHU Brugmann Hospital, and the Quality of the Hospital Care Within the CHU Brugmann Hospital.
Study of Ventilatory Mechanics in Patients With Sickle Cell Anemia
A Study Evaluating the Long-Term Safety of ICA-17043 in Sickle Cell Disease Patients With or Without Hydroxyurea Therapy
PK Study of Ticagrelor in Children Aged Less Than 24 Months, With Sickle Cell Disease (HESTIA4)
Enhancing Use of Hydroxyurea In Sickle Cell Disease Using Patient Navigators
Therapeutic Application of Intravascular Nitrite for Sickle Cell Disease
PK and PD Responses to Oral L-Citrulline in Patients With Sickle Cell Disease
Prevalence of Problematic Use of Equimolar Mixture of Oxygen and Nitrous Oxide and Analgesics in the Sickle-cell Disease
Macrolide Therapy to Improve Forced Expiratory Volume in 1 Second in Adults With Sickle Cell Disease
Haplo T-Cell Depleted Transplantation in High-Risk Sickle Cell Disease
A Brief Laboratory-Based Hypnosis Session for Pain in Sickle Cell Disease
Prasugrel Versus Placebo in Adult Sickle Cell Disease
Evaluating the Safety and Effectiveness of Bone Marrow Transplants in Children With Sickle Cell Disease (BMT CTN 0601)
HLA-Identical Sibling Donor Bone Marrow Transplantation for Individuals With Severe Sickle Cell Disease Using a Reduced Intensity Conditioning Regimen
Sickle Cell Disease (SCD) Decision Aid
Evaluation of Purified Poloxamer 188 in Vaso-Occlusive Crisis of Sickle Cell Disease (EPIC)
Study of Vitamin D in Children With Sickle Cell Disease
Psychometric Evaluation of the IPPAQ in Pediatric Patients With Sickle Cell Disease Hospitalized With Vasoocclusive Pain
Haploidentical Stem Cell Transplant for Patients With Sickle Cell Disease and Prior Stroke or Abnormal Transcranial Ultrasound
Sickle Cell Anemia WE CARE
Improving Emergency Department Management of Adults With Sickle Cell Disease
Transfusion Alternatives Pre-Operatively in Sickle Cell Disease (TAPS)
Exploring Adherence Monitoring in Sickle Cell Disease
Niacin to Improve Blood Flow in People With Sickle Cell Disease
Cardiovascular Complications of Sickle Cell Disease
Bone Marrow Transplantation in Young Adults With Severe Sickle Cell Disease
Quantitative MRI for Patients With Sickle Cell Disease Undergoing Hematopoietic Cell Transplant
Propanolol and Red Cell Adhesion Non-asthmatic Children Sickle Cell Disease
Plasma DNA and Vascular Remodelling in Patients With Sickle Cell Disease
Spectralis HRA+OCT Imaging of the Retina With Autofluorescence in Sickle Cell Disease
A Pilot Study of N-acetylcysteine in Patients With Sickle Cell Disease
Carbon Monoxide Measurement to Screen for Sickle Cell Disease
SALT: Alternative Donor Bone Marrow and Cord Blood Transplantation for High Risk Sickle Cell Disease
Safety and Pharmacokinetics of SANGUINATE™ in Sickle Cell Disease (SCD) Patients
Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia
Liver Fibrosis in Sickle Cell Disease
Evaluation of the Lung Capillary Blood Volume in Children With Sickle Cell Disease
Evaluation of the Hemostatic Potential in Sickle Cell Disease Patients
Longitudinal Changes in Exercise Capacity in Children and Young Adults With Sickle Cell Anemia
Sickle Cell Disease – Stroke Prevention in Nigeria Trial
Exercise Capacity in Pediatric Sickle Cell Anemia
A 3-year, Prospective, Non-interventional, Multicenter Registry in Sickle Cell Disease (SCD) Patients
Links Between Cognitive Functions and Clinical, Biological and Neuroradiological Outcomes in Adults With Sickle Cell Disease.
Molecular Phenotyping of Asthma in Sickle Cell Disease
Phase 1 Study of Zoledronic Acid in Sickle Cell Disease
Biological, Genetic and Environmental Involved in the Complications of Sickle Cell Disease
Community Health Workers and mHealth for Sickle Cell Disease Care
Evaluation of Nocturnal Enuresis and Barriers to Treatment Among Pediatric Patients With Sickle Cell Disease
Sleep and Pain in Sickle Cell Disease
A Study to Assess the Effect of Ticagrelor in Reducing the Number of Days With Pain in Patients With Sickle Cell Disease
Gene Transfer for Patients With Sickle Cell Disease
Vitamin D3 in Patients With Sickle Cell Disease
Collection and Storage of Umbilical Cord Stem Cells for Treatment of Sickle Cell Disease
Risk Factors for Allo-immunization in Sickle Cell Disease
Sickle-cell Disease Registry of the GPOH
Microvascular Blood Flow in Sickle Cell Anemia
Added Value of Speckle Tracking in the Evaluation of Patients With Sickle Cell Disease