A Phase 3 Crossover Trial of Two Formulations of Setmelanotide in Patients With Specific Gene Defects in the Melanocortin-4 Receptor Pathway January 22, 2022checkorphan Learn more about: Pro-opiomelanocortin Deficiency Related Clinical Trial A Phase 3 Crossover Trial of Two Formulations of Setmelanotide in Patients With Specific Gene Defects in the Melanocortin-4 Receptor Pathway Setmelanotide for the Treatment of Early-Onset POMC Deficiency Obesity Recruitment InformationAdministrative Informations