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<p><em>Lambert-Eaton Myasthenic Syndrome (LEMS)</em> is a rare autoimmune disorder which affects the nerve-muscle junction. The major symptoms of LEMS are progressive muscle weakness. Many patients experience other symptoms like dry mouth or impotence. <em>Congenital Myasthenia (CM)</em> is an inherited disorder with similar affects and symptoms. <strong>3,4-Diaminopyridine (DAP)</strong> is an experimental drug that has improved strength in some subjects with (LEMS). There are no other accepted treatments for LEMS and DAP has relatively few side effects.</p>