M. Louise Markert – Primary immunodeficiency disorders

Access Program Information

<p>The primary purpose is to provide access of thymus tissue transplantation to patients who have <strong>immunodeficiency</strong>, <strong>hematologic malignancies,</strong> or <strong>severe autoimmune disease</strong> related to <strong>poor thymic function</strong>. With no thymus function, bone marrow stem cells do not develop into T cells, which fight infection. Eligible participants undergo thymus transplantation and biopsy. Immune suppression may be given depending on the immune status and clinical condition of the participant. Immune function testing is continued for one year post-transplantation.</p>