Children’s Hospital of Philadelphia – Neuroblastoma

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<p>Metaiodobenzylguanidine (MIBG) is a substance that is taken up by <strong>neuroblastoma</strong> or <strong>pheochromocytoma tumor cells.</strong> MIBG is combined with radioactive iodine (131 I)in the laboratory to form a radioactive compound 131 I-MIBG. This radioactive compound delivers radiation specifically to the cancer cells and causes them to die. The purpose of this research protocol is to provides a mechanism to deliver MIBG therapy when clinically indicated, but also to provide a mechanism to continue to collect efficacy and toxicity data that will be provided</p>

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