Baylor College of Medicine – Persistent Hyperinsulinemic Hypoglycemia of Infancy (PHHI)

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The primary objective of this study is to evaluate the utility of [18F]-DOPA PET to provide
improved presurgical planning and distinguish between focal and diffuse forms of HI. The
investigators will perform descriptive analysis, relying on visual analysis to diagnose and
localize a focal lesion. Our findings will be compared to surgical histopathology to
determine sensitivity and specificity or this technique. The investigators will also track
patient surgical outcomes, specifically whether the patient is surgically “cured” or still
requires medical management to control residual hypoglycemia.

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