Dent disease 1
Overview
A rare kidney disease inherited in a X-linked manner. It involves kidney tubule damage which results in progressive kidney dysfunction. There are two types of Dent disease and they differ in the origin of the genetic defect.
Symptoms
- Progressive kidney dysfunction
- High urine calcium level
- Proteinuria
- Nephrocalcinosis
- Kidney tubule damage
- Hyperphosphaturia
- Aminoaciduria
- Nephrolithiasis
- Microglobulinuria
- Polyuria
- Microscopic hematuria
Diagnosis
This medical information about signs and symptoms for Dent's disease has been gathered from various sources, may not be fully accurate, and may not be the full list of Dent disease signs or Dent disease symptoms. Furthermore, signs and symptoms of Dent disease may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed Dent disease symptoms.
Resources
- Minoaciduria: A protein metabolism disorder where excess amino acids are present in the urine.
- Kidney failure: Total failure of the kidneys to filter waste
- Kidney stones: Stone-like calcium deposits in the kidney.
- Microscopic hematuria: microscopic hematuria means presence of red blood cells in urine, but which can be seen only microscopically
- Nephrocalcinosis: A condition characterized by calcium salt deposits in the kidneys which may affect its ability to function. The condition refers to a generally increased level of calcium in the kidneys rather than actual localized deposits such as occurs in kidney stones. It may be caused by such things as high blood calcium levels and tuberculosis. The condition often goes unnoticed until kidney or urinary tract stones form.