Hemophagocytic reticulosis

Overview

Hemophagocytic reticulosis: The abnormal proliferation of reticulum cell (histiocytes) which infiltrate various organs and. Macrophages destroy blood cells causing blood abnormalities. Meningoencephalitis frequently occurs when the histiocytes infiltrate the mininges and cerebral tissue. Symptoms start at birth or soon after and become progressively worse without treatment. Medication can control the condition but a hematopoietic stem cell transplant is needed to achieve remission.

Symptoms

The list of signs and symptoms mentioned in various sources for Hemophagocytic reticulosis includes the 21 symptoms listed below: * Hyperbilirubinemia * Enlarged liver * Enlarged spleen * Fever * Anemia * Pancytopenia * Low fibrinogen level * Pulmonary hemorrhage * High triglyceride level * High ferritin level * Granulocytopenia * Thrombocytopenia * Failure to thrive * Recurring infections * Lymphadenopathy * Hypergammaglobulinemia * Meningoencephalitis * Anorexia * Vomiting * Irritability * Pallor

Causes

* Anemia * Anorexia * Enlarged liver * Enlarged spleen * Failure to thrive * Fever * Irritability * Lymphadenopathy * Meningoencephalitis * Pallor * Pulmonary hemorrhage * Recurring infections * Thrombocytopenia * Vomiting

Diagnosis

The signs and symptom information on this page attempts to provide a list of some possible signs and symptoms of Hemophagocytic reticulosis. This medical information about signs and symptoms for Hemophagocytic reticulosis has been gathered from various sources, may not be fully accurate, and may not be the full list of Hemophagocytic reticulosis signs or Hemophagocytic reticulosis symptoms. Furthermore, signs and symptoms of Hemophagocytic reticulosis may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed Hemophagocytic reticulosis symptoms.