Chromosome 4- Trisomy 4p
Overview
Chromosome 4, trisomy 4p: A rare chromosomal disorder where a portion of chromosome four is duplicated so there is three copies of it instead of the normal two.
Symptoms
The list of signs and symptoms mentioned in various sources for Chromosome 4, trisomy 4p includes the 44 symptoms listed below: * Growth retardation * Obesity * Short stature * Severe mental retardation * Severe language delay * Delayed fine motor skills * Delayed social skills * Infant excessive muscle tone * Reduced muscle tone * Seizures * Abnormal EEG * Small head * Small forehead * Flat forehead * Prominent supraorbital ridges fused across the glabella * Flat nasal bridge * Fleshy nose tip * Monobrow * Enlarged tongue * Irregular teeth * Small pointy jaw * Enlarged ears * Abnormal ear helix * Abnormal ear antihelix * Short neck * Round face in children * Chubby cheeks in children * Triangular face in adults * Poor dentition * Elongated chin * Clinodactyly of fifth fingers * Camptodactyly * Hypoplastic fingernails * Hypoplastic toenails * Small penis * Hypospadias * Undescended testes * Kyphoscoliosis * Hypoplastic nipples * Widely spaced nipples * Absent ribs * Additional ribs * Joint contractures * Behaviour problems
Causes
* Abnormal EEG * Behaviour problems * Camptodactyly * Chubby cheeks in children * Clinodactyly of fifth fingers * Enlarged tongue * Flat nasal bridge * Growth retardation * Hypoplastic nipples * Kyphoscoliosis * Obesity * Reduced muscle tone * Seizures * Short neck * Short stature * Small head * Small penis * Widely spaced nipples
Diagnosis
These home medical tests may be relevant to Chromosome 4, trisomy 4p: * Cold & Flu: Home Testing: * Home Fever Tests * Home Ear Infection Tests * Home Flu Tests