Malformations in neuronal migration

Overview

A rare disorder where the brain fails to develop normally - usually the cerebral cortex is involved. Various parts of the brain can be affected to various degrees depending on what stage of development the defect occurs. Mental retardation is one of the most common symptoms associated with brain malformations.

Symptoms

click here * Lissencephaly - smooth brain * Subependymal heterotopia * Hemimegalencephaly * Corpus callosum anomaly * Schizencephaly

Causes

* Norman-Roberts syndrome * Walker-Warburg syndrome * Cytomegalovirus, congenital * Lennox-Gastaut syndrome * Muscle-eye-brain disease