Osteolysis hereditary multicentric
Overview
A very rare skeletal disorder characterized by bone loss in the hand and foot bones (carpals and tarsals) as well as abnormalities involving the long bones and digits.
Symptoms
* Fusiform enlargement of digits * Contraction of flexion of knee * Contraction of flexion of hip * Contraction of flexion of elbows * Osteoporosis
Causes
* 49,XXXXY syndrome * Acute rheumatic fever * Adducted thumb syndrome recessive form * Alves Castelo dos Santos syndrome * Ampola syndrome * 18p minus syndrome * Acromesomelic dysplasia Hunter Thompson type * Adult hypophosphatasia * Amyoplasia congenital disruptive sequence * Androgen Insensitivity Syndrome