Leber congenital amaurosis 2

Synonyms

2

Overview

Leber congenital amaurosis 2 (LCA2) ia a rare inherited retinal disease (retinal dystrophy) that starts during the fetal stage. Vision impairment is obvious at birth or within months of birth. Type 2 is distinguished from the other forms of this condition by the genetic origin of the defect - chromosome 1, RPE65 gene. 

Symptoms

  • Retinal dysfunction
  • Nystagmus
  • Blindness
  • Sensitivity to light
  • Impaired vision

Causes

  • Eye injury
  • Macular degeneration
  • Age-related macular degeneration
  • Cataracts
  • Glaucoma