Fryns Fabry Remans syndrome

Overview

Fryns-Fabry-Remans syndrome: A rare syndrome characterized by the progressive fusion of the front of the vertebrae as well as the excessive growth of the whole body.

Symptoms

Fused vertebrae Impaired spinal mobility Large hands Large feet Abnormally thick skin on limb

Causes

Diffuse idiopathic skeletal hyperostosis Ankylosing spondylitis Juvenile chronic arthritis