Best vitelliform macular dystrophy

Overview

Vitelliform macular dystrophy or vitelliform dystrophy is a genetic eye disorder that can cause progressive vision loss. This disorder affects the retina, specifically cells in a small area near the center of the retina called the macula. The macula is responsible for sharp central vision, which is needed for detailed tasks such as reading, driving, and recognizing faces

Symptoms

* Mild vision loss in the early stages. * Moderate vision loss in the late stages. * May be symptomatic, but most patients are discovered on routine examinations. * May be associated with choroidal neovascular membrane (CNVM). * Sub-retinal hemorrhage may occur with mild ocular trauma.

Diagnosis

Vitelliform macular dystrophy causes a fatty yellow pigment (lipofuscin) to build up in cells underlying the macula. Over time, the abnormal accumulation of this substance can damage cells that are critical for clear central vision. As a result, people with this disorder often lose their central vision and may experience blurry or distorted vision. Vitelliform macular dystrophy does not affect side (peripheral) vision or the ability to see at night

Treatment

* Treat associated CNVM. * Genetic testing available via Dr. Ed Stone's lab. * Visual potential is usually very good. * Avoid sub-foveal surgery because outcomes can be poor.