Sclerosteosis
Overview
A rare genetic disorder characterized by syndactyly and thickening and overgrowth of bone.
Symptoms
* Progressive bone thickening * Progressive bone overgrowth * Gigantism * Prominent mandible * Asymmetric mandible * Cranial hyperostosis * Occlusion of cranial foramina * Drooping eyelids * Syndactyly of second to third fingers * Deviation of terminal phalanges * Nail dysplasia * Facial distortion * Dental malocclusion * Midfacial hypoplasia * Increased intracranial pressure * Headaches * Intellectual impairment * Premature death may result from increased intracranial pressure * Impaction of medulla oblongata in the foramen magnum
Diagnosis
The signs and symptom information on this page attempts to provide a list of some possible signs and symptoms of Sclerosteosis. This medical information about signs and symptoms for Sclerosteosis has been gathered from various sources, may not be fully accurate, and may not be the full list of Sclerosteosis signs or Sclerosteosis symptoms. Furthermore, signs and symptoms of Sclerosteosis may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed Sclerosteosis symptoms.