Pilot Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Abuse Liability of an Abuse-Deterrent Immediate-Release Formulation (ADAIR)

Narcolepsy

Evaluation of Social Cognition in Patient With Type 1 or Type 2 Narcolepsy Versus Patients With Idiopathic Hypersomnia Narcolepsy Nightmare Study Feasibility Study of At-Home EEG Monitoring for Hypersomnia Spectrometry (MRM) Versus I 125 Radioimmunoassay (RIA) for Quantification of Orexin-A of Patients With Hypersomnolence WAKIX® (Pitolisant) Pregnancy Registry Expanded Access to SUVN-G3031 (Samelisant) for the Treatment of Subjects With Narcolepsy Cardiovascular and Cognitive Implications of Central Disorders of Hypersomnolence and Their Treatments Development and Validation of Pediatric Narcolepsy Patient Reported Outcomes Scale Mainz Register of Patients With Sleep Disorders A Study to Assess the Long-term Efficacy and Safety of AXS-12 (Reboxetine) in Subjects With Narcolepsy A Study to Assess the Efficacy and Safety of AXS-12 (Reboxetine) in Patients With Narcolepsy An Open Label Study of NLS-2 (Mazindol Extended Release) in Subjects With Narcolepsy Evaluate Sunosi® PK in Breast Milk and Plasma of Healthy Postpartum Women Following Single Dose Oral Administration This is a Study to Determine the Effect of Multiple Doses of an Investigational Drug, Taken by Mouth, in People With Narcolepsy-cataplexy. Accepting Both Males and Females Ages of 18 Years to 55 Years. This Study Will be Conducted in the US and Will Require Approximately 13 Weeks Participation. The Value of Combined Detection of Orexin-A, HLA Gene, PSG and MSLT in the Evaluation of Patients With Narcolepsy Four-week Study of the Safety and Efficacy of NLS-2 (Mazindol Controlled Release) in the Treatment of Narcolepsy Child and Adolescent Registry for Participants With Narcolepsy Anesthetic Management of Patients With Chronic Sleep Disorders A Patient-Centric, Prospective, Observational, Non-Interventional Switch Study of XYWAV in Narcolepsy An Interventional Safety Switch Study (IS3) of XYWAV in Narcolepsy A Study to Describe Diagnosis and Treatment Patterns in Narcolepsy Participants in Real Life Practice in Spain Study to Evaluate the Abuse Liability, Pharmacokinetics, Safety and Tolerability of an Abuse-Deterrent d-Amphetamine Sulfate Immediate Release Formulation (ADAIR) An Open Label Study of FT218 in Subjects With Narcolepsy ‘A Profile of Physical Performance Variables in an Out-patient Adult Population With Narcolepsy’ The Nuvigil and Provigil Pregnancy Registry Sleep Disorders of Patients With Diseases of the Nervous System Neurophysiologic Correlates of Hypersomnia Pitolisant to Assess Weekly Frequency of Cataplexy Attacks and EDS in Narcoleptic Patients (HARMONY CTP) Pilot Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Abuse Liability of an Abuse-Deterrent Immediate-Release Formulation (ADAIR) Method of Assessment of Driving Ability in Patients Suffering From Wakefulness Pathologies Safety and Efficacy of THN102 on Sleepiness in Narcoleptic Patients Psychosocial Adjunctive Treatment for Hypersomnia (PATH) The Role of the Circadian System in Neurological Sleep-wake Disorders Observational Study to Evaluate Risks of Side Effects, Drug Abuse and Dependence in Patients Who Received Xyrem ® on Prescription Cardiovascular Variability and Heart Rate Arousal Response in Idiopathic Hypersomnia Clarithromycin for the Treatment of Hypersomnia Patient Narcoleptic Treated With BF2.649 (Pitolisant) in add-on to Sodium Oxybate (HARMONY IV) Efficacy and Safety Study of BF2.649 and BF2.649 Add on Modafinil on Cataplexy in Patients With Narcolespy Effect of Intranasal Administration of Orexine A on IL-6-System, Sleep-Wake-Regulation and Neurocognition Efficacy and Safety of Pitolisant in Pediatric Narcoleptic Patients With or Without Cataplexy, Double-blind Study Followed by a Prolonged Open-label Period Evaluation of Academic and Professional Trajectories of Narcoleptic Patients The Effect of Caffeine on the Narcoleptic Patients Exploration of the Reward System by Functional MRI in Narco-cataplexy Patients With and Without REM Sleep Behavior Disorder Provigil (Modafinil) Study by Taiwan Biotech Co. Study to Assess Patient Reported Outcomes With Armodafinil Treatment for Excessive Sleepiness in Adults With Narcolepsy or Obstructive Sleep Apnea/Hypopnea Syndrome Study of the Academic and Professional Course of Narcoleptic Patients (NARCOSCOL-NARCOVITAE) Extension Study of the Safety and Efficacy of Armodafinil in the Treatment of Patients With Excessive Sleepiness Armodafinil (CEP-10953) for Treatment of Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, or Chronic Shift Work Sleep Disorder Safety and Efficacy of Xyrem Oral Solution (Sodium Oxybate) Compared With Placebo in Narcoleptic Patients A Study of the Safety and Effectiveness of ADX-N05 in the Treatment of Excessive Daytime Sleepiness Efficacy and Safety Study of BF2.649 in the Treatment of Excessive Daytime Sleepiness in Narcolepsy Study Assessing Effects of JZP-110 on Driving Performance in the Treatment of Excessive Sleepiness in Narcolepsy “A Long-Term Safety Study of JZP-110 in the Treatment of Excessive Sleepiness in Subjects With Narcolepsy or OSA” A Multicenter Study of the Efficacy and Safety of Xyrem With an Open- Label Pharmacokinetic Evaluation and Safety Extension in Pediatric Subjects With Narcolepsy With Cataplexy Once-Nightly Sodium Oxybate for Treatment of Excessive Daytime Sleepiness and Cataplexy in Narcolepsy Assess the Safety and Effectiveness of PROVIGIL Treatment in Children and Adolescents With Excessive Sleepiness A Study of the Efficacy and Safety of JZP-258 in Subjects With Narcolepsy With Cataplexy Narcolepsy – New Potential Treatment Clinical Outcomes in Narcolepsy and Cataplexy: An Evaluation of Reboxetine Treatment (CONCERT) Long Term Open Label Study in Narcolepsy With BF2.649 (Pitolisant) Evaluation of the Efficacy of Sodium Oxybate (Xyrem®) in Treatment of Post-traumatic Narcolepsy and Post-traumatic Hypersomnia Expanded Access Program to Provide Treatment With Pitolisant to Adult Patients in the U.S. With Excessive Daytime Sleepiness Associated With Narcolepsy With or Without Cataplexy Investigation of Clinical Feature and Brain Function in Narcoleptic Patients A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TAK-925 in Healthy Volunteers and Patients With Narcolepsy Microglial Activation in Narcolepsy Type 1: Positron Emission Tomography (PET) Study in [18F] DPA-714 A Study to Evaluate Safety, and Efficacy of SUVN-G3031 in Patients With Narcolepsy With and Without Cataplexy Trial of Xyrem® (Sodium Oxybate) for the Treatment of Narcolepsy Safety and Efficacy Study of Armodafinil (CEP-10953) in the Treatment of Excessive Sleepiness Associated With Narcolepsy Awareness and Self-Compassion Enhancing Narcolepsy Treatment A Study of the Safety and Effectiveness of ADX-N05 for Excessive Daytime Sleepiness in Subjects With Narcolepsy “Twelve-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in Narcolepsy” Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Armodafinil in Children and Adolescents With Excessive Sleepiness Associated With Narcolepsy Trial Comparing Effects of Xyrem Taken Orally and Modafinil With Placebo in Treating Daytime Sleepiness in Narcolepsy Narcolepsy Protect Against Alzheimer’s Disease? PROVIGIL® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Narcolepsy or Obstructive Sleep Apnea/Hypopnea Syndrome TElemedicine for NARcolepsy Swiss Primary Hypersomnolence and Narcolepsy Cohort Study Body Weight Regulation in Patients With Narcolepsy Metabolism Characteristics in the Children With Narcolepsy A Web-based Observational Study of Patient-reported Outcomes in Adults With Narcolepsy Risk of Narcolepsy Associated With Administration of H1N1 Vaccine A Safety and Effectiveness Study of a Single Dose of JNJ-17216498 in Patients With Narcolepsy A Study to Evaluate the Safety and Efficacy of TS-091 in Patients With Narcolepsy Xyrem and Brain Dopamine in Narcolepsy Effectiveness Of The Drug GSK189254 In Treating Patients With Narcolepsy Study of PROVIGIL ® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Narcolepsy