Darier’s disease
Overview
Darier's disease is a genetic disorder discovered by French dermatologist Ferdinand-Jean Darier. Darier's is characterized by dark crusty patches on the skin, sometimes containing pus. The crusty patches are also known as keratotic papules, keratosis follicularis or dyskeratosis follicularis.
Symptoms
* In this case the skin get injured & leads to occur over the oily areas of the skin like scalp margins, forehead, ears, around the nostrils and the sides of nose, eyebrows etc. * Some common features of this disease are itching, little brownish, rough-topped bumps may develop on the skin. And also small pits occur on the palms of the hands & the soles of the feet. * In dariers disease an unpleasant smell may occur from patient. * The ducts of the salivary glands in the cheeks may be obstructed, resulting in acute swelling of the parotid gland.
Causes
Causes of Dariers Disease * The main cause of this disease is abnormality in the gene, environmental factors, heat, humidity, and exposure to sunlight * And the other main cause of this disease is because of the disturbance in the way of the skin cells that are joined together. * This disease inherited from family to family, there are 50% chance that each child of an affected parents may inherit the problem. * In summer a red eruption of the skin occurs due to heat & humidity.
Treatment
Treatment of choice for severe cases is oral retinoids. During flares, topical or oral antibiotics may be administered. Cyclosporin and topical corticosteroids have been used during acute flares. Some patients are able to prevent flares with use of topical sunscreens and oral vitamin C. * benzoyl peroxide