Alves Castelo dos Santos syndrome
Overview
A rare syndrome characterized by hair, eye, skin and spinal abnormalities.
Symptoms
- Short stature
- Sparse scalp hair
- Absent scalp hair
- Decreased sweating
- Dry skin
- Dysplastic toenails
- Thick toenails
- Grooved toenails
- Genu valgum
- Hyperkeratosis
- Absent eyebrows
- Sparse eyebrows
- Cataract
- Decreased body hair
- Increased body hair
- Increased carrying angle of the elbows
- Scoliosis
- Short nose
- Small nose
- Spina bifida occulta
- Webbed fingers
- Telecanthus
- Small jaw
- Narrow nasal bridge
- Joint anomaly
- Protruding lips
- Proximally set thumb
- Thin fingernails
- Hyperconvex fingernails
- Abnormal tooth shape
- Small head
- Missing teeth
- Tooth enamel anomalies
- Muscle wasting
- Diabetes mellitus
- Cleft lip
- Cleft palate
- Narrow eye slits
- Kyphoscoliosis
- Abnormal nails
- Easy bruising after minor skin trauma
- Easy scarring after minor skin trauma
- Abnormal dermatoglyphics
- Ectodermal dysplasia
- Eye anomalies