Kimura disease
Overview
Kimura disease: A rare inflammatory disorder involving the development of clusters of nodules on the head and neck area. Kidney symptoms also usually occur.
Symptoms
The list of signs and symptoms mentioned in various sources for Kimura disease includes the 6 symptoms listed below: * Translucent nodules around ear * Translucent nodules in head area * Translucent nodules in neck area * Membranous glomerulonephritis * Increased number of eosinophils in blood * Excess protein in urine Note that Kimura disease symptoms usually refers to various symptoms known to a patient, but the phrase Kimura disease signs may refer to those signs only noticable by a doctor.
Causes
Excess protein in urine
Diagnosis
SKIN THICKENING: DIAGNOSTIC WORKUP (Algorithmic Diagnosis of Symptoms and Signs) In cases of diffuse thickening of the skin, a thyroid profile with T 3 , T 4 , and TSH should be done. This should also identify hypothyroidism. A positive ANA test with a speckled pattern will help identify scleroderma, but a skin biopsy should also be done. An antisclerodermal antibody titer is also useful if available. Esophageal motility studies will be helpful in early diagnosis. A skin biopsy will help identify many of the other conditions mentioned above. Urine for porphyrins will help identify porphyria.