Intermittent Preventive Treatment for Malaria in Patient With Sickle Cell Disease

Sickle cell anemia

Suvankar Majumdar – Sickle cell anemia

Inflammation, Platelets and Sickle Cell Disease Safety Evaluation of DREPADOM – Home Care Services and Hospitalizations for Sickle Cell Disease Patients Tocilizumab Acute Chest Osteopathic Manipulation in the Management of Pain Associated With Sickel Cell Disease GBT021601-022: A Study of GBT021601 in Participants With Sickle Cell Disease (SCD) Motixafortide and Natalizumab to Mobilize CD34+ Hematopoietic Stem Cells for Gene Therapies in Sickle Cell Disease (SCD) Minocycline In Neurocognitive Outcomes – Sickle Cell Disease Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle Cell Disease Using PET Mindfulness and Yoga Therapy for Acute Pain in Sickle Cell Disease Brain Structure and Neurocognitive Development in Sickle Cell Disease; a Longitudinal Cohort Study (BRICK Study) Safety, Efficacy, Pharmacokinetic, and Pharmacodynamic Study of ALXN1820 in Adult Participants With Sickle Cell Disease Resolution of Sickle Cell Leg Ulcers With Voxelotor Cannabinoids for the Reduction of Inflammation and Sickle Cell Related Pain Pilates Physical Activity in Sickle Cell Disease Evaluation of Low-cost Techniques for Detecting Sickle Cell Disease and β-thalassemia in Nepal Characteristics of Patients With Sickle Cell Disease Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease L-Arginine in Children Having Sickle Cell Disease With Increased Tricuspid Regurgitant Jet Velocity Acceptability of a New Paediatric Formulation of Hydroxycarbamide in Children With Sickle Cell Disease. Crizanlizumab Improves Tissue Oxygen Supply Demand Matching in Patients With Sickle Cell Anemia Feasibility and Preliminary Efficacy of Acceptance and Commitment Therapy (ACT) for Sleep Disturbances in Adults With Sickle Cell Disease (SCD) BEACON: A Study Evaluating the Safety and Efficacy of BEAM-101 in Patients With Severe Sickle Cell Disease Hydroxyurea and EPO in Sickle Cell Disease Study of MGTA-145 and Plerixafor in Patients With Sickle Cell Disease Primary Prevention of Stroke in Children With Sickle Cell Anaemia in Nigeria in the Community A Phase 2/3 Study in Adult and Pediatric Participants With Sickle Cell Disease (SCD) A Study to Evaluate an Electronic Patient Diary in Adult Participants With Sickle Cell Disease Research Study Investigating How Well NDec Works in People With Sickle Cell Disease Hemoglobinopathy Nursing Program and Pediatric Nursing Students Low Dose Iron Chelation as TReatment of Oxidative Damage in Sickle Cell Disease RElated Haplo-DonoR Haematopoietic stEm Cell Transplantation for Adults With Severe Sickle Cell Disease Empowering Adolescents and Young Adults With Sickle Cell Disease as Partners in Treatment Decision Making (EMPOWER-AYA) TMLI and Alemtuzumab for Treatment of Sickle Cell Disease Study of Erythrocyte Parameters and Hypercoagulability in Sickle Cell Disease (SCD-TGA) Early Life Exposures Among Children With Sickle Cell Disease Sickle Cell Improvement: Enhancing Care in the Emergency Department Glutamine Role in Preventing Vaso-occlusive Crisis Among SCD Patients Exercise in Child Health Addition of JSP191 (C-kit Antibody) to Non-myeloablative Hematopoietic Cell Transplantation For Sickle Cell Disease and Beta-Thalassemia A Gene Transfer Study Inducing Fetal Hemoglobin in Sickle Cell Disease (GRASP, BMT CTN 2001) A Study to Evaluate the Long-term Safety of Inclacumab Administered to Participants With Sickle Cell Disease The Montreal Cognitive Assessment.Test in Adults With Sickle Cell Disease Cognitive Remediation Intervention to Prepare for Transition of Care Study of Crizanlizumab for Prevention of Silent Cerebral Infarcts in SCA Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Severe Sickle Cell Disease (SCD) COVID-19 Testing in Underserved and Vulnerable Populations CHOICES3: Sickle Cell Disease Parenting CHOICES Hyperbaric-oxygen Therapy (HBOT) Versus Placebo for Treating Vaso-Occlusive Crisis (VOC) in Sickle Cell Disease (SCD) Promoting Utilization and Safety of Hydroxyurea Using Precision in Africa Bone Pain in Adults With Sickle Cell Disease A Phase 1/2, Open-Label, Dose Escalating Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AB1 in Adult Patients With Sickle Cell Disease (SCD) Low Dose Aspirin for Preventing Intrauterine Growth Restriction and Preeclampsia in Sickle Cell Pregnancy (PIPSICKLE) Red Blood Cell – IMProving trAnsfusions for Chronically Transfused Recipients Adding Azathioprine/Hydroxyurea Preconditioning to Alemtuzumab/TBI to Reduce Risk of Graft Failure in MSD HSCT in Adult SCD Patients Voxelotor Neurocognitive Function Study Voxelotor Cerebral Hemodynamics Study SCD Fit Homebase Program Cutaneous Hydration Assessment in SCD The Predictive Capacity of Machine Learning Models for Progressive Kidney Disease in Individuals With Sickle Cell Anemia Avascular Bone Necrosis in Sickle Cell Disease: a Pediatric Study. Preservation and Transfer of HBV Immunity After Allogeneic HSCT for SCD. Nasopharyngeal Bacterial Carriage and Antibiotic Resistance in Children With Sickle Cell Disease in Ile-De-France Hemolysis Related Complications in SCD. A Phase II Study With Voxelotor Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of FTX-6058 Observational Study of Dietary Intake and Dietary Behaviors in Adults With Sickle Cell Disease Severe Acute Respiratory Syndrome CoV 2 COVID-19 Survey and Vaccination Coverage in the Sickle Cell Population in Ile-De-France Cooperative Assessment of Late Effects for SCD Curative Therapies COVID-19 Vaccine Response in Sickle Cell Disease Sickle Cell Disease Obstetric Multi-Disciplinary Care Programme: Prospective Multi-Centre Cohort Study Safety, Tolerability and Pharmacokinetics of FTX-6058 Feasibility and Efficacy of Attentional-Control Training in Sickle Cell Disease Pharmacokinetics and Pharmacodynamics of Rifaximin Novel Formulations in Patients With Sickle Cell Disease Hydoxycarbamide and L-Carnitine Therapy in Sickle Cell Anemia Interest of Famotidine in Children With Sickle Cell Disease A Study Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Crovalimab as Adjunct Treatment in Prevention of Vaso-Occlusive Episodes (VOE) in Sickle Cell Disease (SCD) Long-term Comparative Cerebrovascular Outcome After Transplantation vs Standard Care in Sickle Cell Anemia Integrative Medicine in Pain Management in Sickle Cell Disease A Study to Evaluate GBT021601 in Single and Multiple Doses in Healthy Participants THromboprophylaxis In Sickle Cell Disease With Central Venous Catheters (THIS) A Study Evaluating the Efficacy and Safety of Mitapivat (AG-348) in Participants With Sickle Cell Disease Prospective, Observational Study in Sickle Cell Disease Patients on Crizanlizumab Treatment in Middle East Countries and India Losartan for Diffuse Myocardial Fibrosis in Sickle Cell Disease A Study of FT-4202 in Patients With Thalassemia or Sickle Cell Disease A Study to Evaluate GBT021601-012 Single Dose and Multiple Dose in Participants With Sickle Cell Disease (SCD) Functional and Mechanistic Characterization of Limb Ulcers in Patients With Sickle Cell Disease A Study to Assess the Safety and Efficacy of Inclacumab in Participants With Sickle Cell Disease Experiencing Vaso-occlusive Crises PET Imaging of Vaso-Occlusive (VOC) in SCD Retrospective Real World Oxbryta® Data Collection and Analysis Study Oxbryta® Product Registry An Observational Study Designed to Evaluate the Effect of Oxbryta in Individuals With SCD A Study of a Single Dose of Inclacumab to Reduce Re-admission in Participants With Sickle Cell Disease and Recurrent Vaso-occlusive Crises Observational Prospective Study Measuring the Impact of the Use of a Hypnotic Script Associated With Virtual Reality on the Pain of the Child’s Sickle Cell During a Vaso-occlusive Crisis Health Literacy – Neurocognitive Screening in Pediatric SCD A Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics and Efficacy of Crovalimab for the Management of Acute Uncomplicated Vaso-Occlusive Episodes (VOE) in Participants With Sickle Cell Disease (SCD). Prevalence and Pathophysiology of Systemic Arterial Pressure Abnormalities in Childhood Sickle Cell Disease Hybrid Effectiveness-Implementation Trial of Guided Relaxation and Acupuncture for Chronic Sickle Cell Disease Pain Home-Based Intervention for Chronic Pain in Adults With Sickle Cell Disease Distracting Through Procedural Pain and Distress Evaluation of Left Ventricular Function by Speckle Tracking Echocardiography in Patient Hospitalised in Intensive Care Unit for Vaso-occlusive Crisis EDIT-301 for Autologous HSCT in Subjects With Severe Sickle Cell Disease Sickle Cell Disease Treatment With Arginine Therapy (STArT) Trial Study of Biological Markers in Children With Sickle Cell Disease Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease Peripheral Blood Stem Cell Collection From Patients With Sickle Cell Disease (SCD) Using Plerixafor A Phase 2a Study to Assess Efficacy and Safety of VIT-2763 in Subjects With Sickle Cell Disease Stroke Prevention in Young Adults With Sickle Cell Anemia The Afolabi Stroke Registry for Children and Young Adults With SCD in Northern Nigeria Sickle Cell Disease, Neurocognitive Disorders, Social Participation Pre-transplant Immunosuppression and Donor Stem Cell Transplant for the Treatment of Severe Hemoglobinopathies Fitness Trial in Adults With Sickle Cell Disease (SCD Fit): A Feasibility Study Transplantation of Clustered Regularly Interspaced Short Palindromic Repeats Modified Hematopoietic Progenitor Stem Cells (CRISPR_SCD001) in Patients With Severe Sickle Cell Disease Evaluation of Virtual Reality to Save Morphinic in the Treatment of Vaso-occlusive Seizures of Sickle Cell Patients Consulting in the Emergency Room Interest of Nutritional Care of Children With Sickle Cell Disease on Bone Mineral Density and Body Composition Expanded Access Protocol for Pediatric Patients With Sickle Cell Disease Who Have No Alternative Treatment Options Physical Rehabilitation in Sickle Cell Anemia ESCORT-HU Extension: European Sickle Cell Disease Cohort – Hydroxyurea – Extension Study Vitamin D Status in Children With Sickle Cell Disease Living in Lyon, France The Longitudinal Relationship of HU Adherence to HRQOL, Barriers to Adherence and Habit in SCD. An mHealth Strategy to Improve Medication Adherence in Adolescents With Sickle Cell Disease Home-based Assessment of PRO Measures in SCD Using A Smartphone App Platform: A Feasibility Study Adherence to HU and HRQOL in Patients With Sickle Cell Disease: An Intervention Study Using HU-Go App Pharmacokinetics and Safety of Endari (L-glutamine) in Sickle Cell Disease Patients Obesity in Pediatric Sickle Cell Disease: A New Phenomenon Evaluation of Therapeutic Adherence to Inciting Spirometry in Sickle Cell Patients An Indian Multi-centric Phase IV Study to Assess the Safety of Crizanlizumab in Sickle Cell Disease Patients Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study Effects of Prebiotics on Gut Microbiome in Patients Undergoing HSCT A Study of FT-4202 in Adults and Adolescents With Sickle Cell Disease Long-term Follow-up of Subjects With Sickle Cell Disease Treated With Ex Vivo Gene Therapy Lidocaine for Sickle Cell Crisis Pain in the Emergency Department Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects With Stable Sickle Cell Disease: An Extension of a Phase I Pilot Study of Mitapivat Building Adaptive Coping and Knowledge to Improve Daily Life Utilizing A Single Session Problem-Solving Intervention With Caregivers of Pediatric Patients Receiving Chronic Transfusion to Treat Sickle Cell Disease US Phase I Study of ECT-001-CB in Patients With Sickle-Cell Disease Designing an Implementation Strategy for Delivering Routine Mental Health Screening and Treatment Implementing an Individualized Pain Plan (IPP) for ED Treatment of VOE’s in Sickle Cell Disease PINPOINT: Gaming Technology for SCD Pain Voxelotor Sickle Cell Exercise Study SELF-BREATHE RCT for Chronic Breathlessness Medication Adherence and Non-adherence in Adults With Rare Disease Pilot Study PBSCT With TCRab Depletion for Hemoglobinopathies A Study Aimed to Assess the Needs of Subjects With Sickle Cell Disease and Healthcare Professionals Managing Sickle Cell Disease Patients in Selected Nigerian Centres A Stress and Pain Self-management m-Health App for Adult Outpatients With Sickle Cell Disease Red Cell Half Life Determination in Patients With and Without Sickle Cell Disease Isoquercetin in Sickle Cell Anemia A Study of IMR-687 in Subjects With Sickle Cell Disease Study of Safety and Efficacy of Genome-edited Hematopoietic Stem and Progenitor Cells in Sickle Cell Disease (SCD) Dose Ranging Study of Benserazide in Thalassemia Intermedia Red Blood Cell Survival in Sickle Cell Disease Sickle Cell Disease and the Genomic Needs of Parent and Pediatric Stakeholders A Longitudinal Survey Study on Living With Sickle Cell Disease in the COVID-19 Pandemic Evaluation of Impact of Disease on Quality of Life, Education and Socio-professional Integration of Adults and Parents of Children Living With Sickle- Cell Disease in France Low Dose Ketamine and Acute Pain Crisis Preliminary Feasibility and Efficacy of Behavioral Intervention to Reduce Pain-Related Disability in Pediatric SCD Improving Scientific Rigor of Renal Clinical Endpoints for Sickle Cell Anemia Actigraphy Improvement With Voxelotor (ActIVe) Study Venous Thrombosis Biomarkers in Sickle Cell Disease and Sickle Cell Trait A Voxelotor for Sickle Cell Anemia Patients at Highest Risk for Progression of Chronic Kidney Disease Reduced Intensity Transplantation for Severe Sickle Cell Disease Prevalence of Osteoporosis in Sickle Cell Disease Study of Melphalan Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant Patients Study of Clofarabine and Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation (HCT) Improving Quality by Maintaining Accurate Problems in the EHR Study of Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation Study of an Intervention to Improve Problem List Accuracy and Use Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion Pharmacokinetic (PK) and Pharmacodynamics (PD) Study of Ilera Specific Products Study of Thiotepa and TEPA Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant Patients Hospital-Based Program for Treatment of Severe Cardiopulmonary Disease With Inhaled Nitric Oxide Clinical Transplant-Related Long-term Outcomes of Alternative Donor Allogeneic Transplantation Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions CD34+Selection for Partially Matched Family or Matched Unrelated Adult Donor Transplant Kid Cards: Teaching Kids About Medicines Coordinated HEalthcare for Complex Kids PATient Navigator to rEduce Readmissions CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation Clinical Diagnosis of Teenagers Admitted to Pediatric Departments Study of Allogeneic Bone Marrow Transplantation Using Matched, Related Donors in Patients With Nonmalignant Hematologic Disorders Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload Stem Cell Transplant for Hemoglobinopathy Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies Pilot Study for Patients With Poor Response to Deferasirox Developing the Family Map: Looking at Communal Coping Comparison of Two Methods of Transfusion for Stroke Prevention in Sickle Cell Validating Pain Scales in Children and Young Adults Investigation of the Genetics of Hematologic Diseases Point-of-Delivery Prenatal Test Results Through mHealth to Improve Birth Outcome Blood Transfusions in Thalassemia Patients, Complications and Adverse Effects Deferoxamine for Sickle Cell Chronic Leg Ulcer Treatment Hyperbaric Oxygen Therapy in Sickle Cell Pain Oral Magnesium Pidolate, Hemoglobin SC Disease, MG Pidolate High-Tc Susceptometer to Monitor Transfusional Iron Overload Allogeneic Stem Cell Transplantation Following Chemotherapy in Patients With Hemoglobinopathies Study Of Efficacy,Safety of Combined Deferasirox and Deferiprone Versus Combined Deferiprone and Desferal In Conditions of Iron Overload Measures of Respiratory Health (MRH) Screening for Subjects to Participate in Studies of Blood Disorders SCD-PROMIS: A Software Platform to Enhance Self-efficacy and Patient-provider Engagement for Patients With Sickle Cell Pain Ranibizumab for Neovascularization in Sickle Cell Retinopathy Allogeneic SCT of CordIn™, in Patients With Hemoglobinopathies Use of a Mobile-based App for SCD Patients Allo-HCT MUD for Non-malignant Red Blood Cell (RBC) Disorders: Sickle Cell, Thal, and DBA: Reduced Intensity Conditioning, Co-tx MSCs Does IV Acetaminophen Reduce Opioid Requirement in Pediatric Patients With Acute Sickle Cell Crises? Allogeneic Mixed Chimerism Stem Cell Transplant Using Campath for Hemoglobinopathies & Bone Marrow Failure Syndromes Preventing Sickle Cell Kidney Disease Effects of Transfusion of Older Stored Red Cells Feasibility Study of Unfractionated Heparin in Acute Chest Syndrome Extension Study of ACTIQ Treatment for Children and Adolescents With Breakthrough Pain A Study to Compare if the Uptake of Ticagrelor in the Body Differs When Different Tablets Are Administered A Single-Dose Relative Bioavailability Study Of GBT440 300 mg Capsules in Healthy Subjects Drug Interaction Study of GBT440 With Caffeine, S-warfarin, Omeprazole, and Midazolam in Healthy Subjects A Relative Bioavailability Study of a Prasugrel Orally Disintegrating Tablet Daily Vitamin D for Sickle-cell Respiratory Complications Nitrous Oxide Analgesia Vaso-occlusive Crisis Abciximab (ReoPro) as a Therapeutic Intervention for Sickle Cell Vaso-Occlusive Pain Crisis Prevalence Of Microalbuminuria Among Children Suffering From Sickle Cell Nephropathy and Sickle Cell/Beta-Thalassemia Bone Marrow Transplant From Donor Using Less Toxic Conditioning for Patient With High Risk Hemoglobinopathies Hydoxyurea Exposure in Lactation A Pharmacokinetics Study (HELPS) Algorithm for Apherisis Monitoring and Prescription Assistance in Sickle Cell Patients (ALGODREP) Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation A Long-term Follow-up Study in Subjects Who Received CTX001 Vitamin D for Sickle-cell Respiratory Complications Pilot Study of Fructose for Sickle Cell Crisis Genes Influencing Iron Overload State Safety Study of MP4CO in Adult Sickle Cell Patients A Study of IMR-687 in Healthy Adult Volunteers Cerebral Oxygen Metabolism in Children Treatment of Adult Patients With Hemoglobin SC Disease (SCYTHE) Bone Marrow Transplant From Related Donor for Patients With High Risk Hemoglobinopathies A Trial to Assess Haploidentical T-depleted Stem Cell Transplantation in Patients With SCD Choosing Opioid Management for Pain and Analyzing Acute Chest Syndrome (ACS) Rates Equally Effect of Inhaled Nitric Oxide in Acute Chest Syndrome (INOSTA Study) The Use of Warmed Saline in Vaso-occlusive Episodes Hydroxyurea Therapy: Optimizing Access in Pediatric Populations Everywhere Study of GMI-1070 for the Treatment of Sickle Cell Pain Crisis Novel Use Of Hydroxyurea in an African Region With Malaria Pharmacokinetics of Oral Hydroxyurea Solution Bi-Level Positive Airway Ventilation for Acute Chest Syndrome Mobile-Directly Observed Therapy on Adherence to Hydroxyurea A Comprehensive Care Plan for Pediatric Patients With Vaso-Occlusive Crises Glutamine Therapy for Hemolysis-Associated Pulmonary Hypertension A Pilot Study of HSCT for Patients With High-risk Hemoglobinopathy Using a Nonmyeloablative Preparative Regimen Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies Longterm Follow-up of Subjects With Hemoglobinopathies Treated With Ex Vivo Gene Therapy Intravenous Magnesium for Sickle Cell Vasoocclusive Crisis Invasive Infections in Children With Hemoglobinopathies Intranasal Fentanyl Versus Intravenous Morphine in the Treatment of Severe Painful Sickle Cell Crises in Children Preventing Acute Chest Syndrome by Transfusion Feasibility Study Angiotensin-converting Enzyme Inhibitors and Early Sickle Cell Renal Disease in Children Cerebrovascular Reserve and White Matter Disease in Patients With Chronic Anemia Hydroxyurea Management in Kids: Intensive Versus Stable Dosage Strategies Stem Cell Transplantation After Reduced-Dose Chemotherapy for Patients With Sickle Cell Disease or Thalassemia Use of Mobile Technology for Intensive Training in Medication Management Silent Cerebral Infarct Transfusion Multi-Center Clinical Trial Nitric Oxide and Sickle Cell Pain Near Infrared Spectroscopy in Sickle Cell Pediatric Patients sPLA2 in EBC During Acute Chest Syndrome Re-Aiming at Hydroxyurea Adherence for Sickle Cell With mHealth Ketamine Infusion for Acute Sickle Cell Crisis in the Emergency Department A Phase I/II Trial of Recombinant-Methionyl Human Stem Cell Factor (SCF) in Adult Patients With Sickling Disorders Disseminating NIH Evidence Based Sickle Cell Recommendations in North Carolina Is the Preoperative Preparation of Sickle Cell Patients Optimal: Assessment of Practices and Post-operative Complications Inhaled Mometasone to Promote Reduction in Vasoocclusive Events 2 Endothelial Monocyte-activating Polypeptide-II in Egyptian Sickle Patients Losartan for Sickle Cell Kidney Disease Early Diagnosis of Sickle Acute Chest Syndrome Using a Combination of Plasma Bimarkers and Chest Imaging Home Based Massage and Relaxation for Sickle Cell Pain Treatment of Sickle Cell Patients Hospitalized in Pain Crisis With Prophylactic Dose Low-molecular-weight Heparin (LMWH) Versus Placebo Adjuvant Low-dose Ketamine in Pediatric Sickle Cell Vaso-occlusive Crisis Optimizing Hydroxyurea Therapy in Children With SCA In Malaria Endemic Areas Novel Dose Escalation to Predict Treatment With Hydroxyurea EXTEND EXpanding Treatment for Existing Neurological Disease HSCT For Patients With High Risk Hemoglobinopathies Using Reduced Intensity Bone Marrow for Hemoglobinopathy Research Gaming Technology to Engage Adolescent Sickle Cell Patients in Pain Management Ketamine Sickle Cell Disease Phosphodiesterase Type-5 Inhibitor Therapy in Sickle Cell People With Pulmonary Hypertension Methadone in Pediatric and Adult Sickle Cell Patients Transillumination Device for Peripheral Intravenous Placement in Patients With Sickle Cell Disease (PERFID) Hydroxyurea and Magnesium Pidolate to Treat People With Hemoglobin Sickle Cell Disease Regional Anesthesia for Sickle Cell Crisis Using Ultrasound in The Emergency Department: Phase I Phase II Randomized Trial:Arginine Butyrate Plus Standard Local Therapy in Patients With Refractory Sickle Cell Ulcers Treatment of Hemoglobin SC Disease Fetal Hemoglobin Induction Treatment Metformin Hydroxyurea Optimization Through Precision Study Realizing Effectiveness Across Continents With Hydroxyurea (REACH) Evaluation of Non-invasive Endothelial Function in Children Sickle by Vascular Ultrasound Inhaled Nitric Oxide for Pediatric Painful Sickle Crisis TAPS2 Transfusion Antenatally in Pregnant Women With SCD Ketamine for Acute Painful Crisis in Sickle Cell Disease Patients Dissemination and Implementation of Stroke Prevention Looking at the Care Environment THE IMPROVE TRIAL: Improving Pain Management and Outcomes With Various Strategies of Patient-Controlled Analgesia (PCA) Dense Red Blood Cells in Sickle Cell Children Phase 2 Study of MP4CO to Treat Vaso-occlusive Sickle Crisis Sickle Cell Anemia Screening and Prevention in Northern Israel Carbon Monoxide Monitor for the Measurement of End-Tidal Carbon Monoxide Levels in Children With or Without Hemolysis Ameliorating Attention Problems in Children With Sickle Cell Disease (SCD) Pulmonary Hypertension, Hypoxia and Sickle Cell Disease Cognitive Behavioral Therapy and Real-time Self-management Intervention for SCD Via Mobile Applications Collection of Human Biospecimens for Basic and Clinical Research Into Alpha Globin Variants Multicenter Observational Study on Myocardial Iron Overload in 3 Multitransfused Populations Bone Marrow Transplantation, Hemoglobinopathies, SCALLOP Evaluation of Sickle Cell Liver Disease Stigma, Self-management, & Quality of Life in SCD Combined Use of a Respiratory Broad Panel Multiplex PCR and Procalcitonin to Reduce Antibiotics Exposure in Hospitalized Sickle-cell Adults With Acute Chest Syndrome. Blood Collection for Research Related to Certain Diseases Involving Blood Vessels Intravenous Gammaglobulin for Sickle Cell Pain Crises Comparison of Patient Controlled Analgesia (PCA) Versus Bolus Narcotic Therapy for the Treatment of Vaso-Occlusive Crisis (VOC) Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias Pharmacokinetics and Pharmacodynamics Study of SEG101 (Crizanlizumab) in Sickle Cell Disease (SCD) Patients With Vaso- Occlusive Crisis (VOC) FOCUS for Pediatric Sickle Cell Disease and Cancer SIKAMIC (SIklos on Kidney Function and AlbuMInuria Clinical Trial) Long Term Follow up in Sickle Cell Patients Treated by Hydroxyurea Sickle Cell Hemoglobinopathies and Bone Health Allogeneic Bone Marrow Transplantation for the Treatment of Genetic Disorders of Erythropoiesis Evaluation of the Impact of Renal Function on the Pharmacokinetics of SIKLOS ® (DARH) HRV-B for Symptom Management in Sickle Cell Patients Sickle Cell Pain: Intervention With Capsaicin Exposure Motivations, Expectations, and Decision-making of Sickle Cell Patients in Clinical Research A Phase 1 Study of Continuous Intravenous L-citrulline During Sickle Cell Pain Crisis or Acute Chest Syndrome Topical Sodium Nitrite for Chronic Leg Ulcers in Adult Patients With Blood Disorders Pediatric Hydroxyurea Phase III Clinical Trial (BABY HUG) Follow-up Observational Study II Protocol Primary Prevention of Stroke in Children With SCD in Sub-Saharan Africa II RHD Genotype Matching for Anti-D Validation of the Sickle Cell Disease Pain Burden Interview RH Genotype Matched RBC Transfusions A Phase – IIa – IIb, Trial to Study the Safety, Tolerability and Efficacy of Memantine as a Long-term Treatment of SCD Early Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell Transplantation Monocytic Expression of Heme Oxidase-1 (HO-1) in Sickle Cell Patients and Correlation With the Humoral Immune Response to Vaccine and With Allo-immunization. Albuminuria Reduction With Renin Angiotensin System Inhibitors in SCA Patients Substudy of CADRE: for People With Extreme Phenotype: BIOCADRE Sevuparin Infusion for the Management of Acute VOC in Subjects With SCD Evaluation of the AMICUS RBCx System in Sickle Cell Patients Losartan to Reverse Sickle Nephropathy Evaluation of Repeat Administration of Purified Poloxamer 188 Prevention of Vaso-occlusive Painful Crisis by Using Omega-3 Fatty Acid Supplements Age of Blood in Sickle Cell Transfusion Study to Assess the Effect of Long-term Treatment With GBT440 in Participants Who Have Completed Treatment in Study GBT440-031 Sub-dissociative Intranasal Ketamine for Pediatric Sickle Cell Pain Crises Sickle Cell Uric Acid (SCUA) – Cohort Repository Effectiveness of New Analgesic Strategy Compared to the Usal Antalgic Strategy Self-Management for Youth and Families Living With SCD – SMYLS Rejuvesol® Washed RBC in Sickle Cell Patients Requiring Frequent Transfusions Hydroxyurea and Transfusion Hydroxyurea Adherence for Personal Best in Sickle Cell Treatment: HABIT Prevention Of Morbidity In Sickle Cell Disease Pilot Phase Quality of Care of Children With Sickle Cell Disease (SCD) Screened at Birth in France A Dose Escalation Study of Intravenous L-citrulline in Steady-state Sickle Cell Disease Identifying Barriers and Strategies to Support Self-efficacy for Medication Adherence With Text Messaging IMPACTS Trial: Investigation of the Modulation of Phospholipase in Acute Chest Syndrome Evaluating Thromboelastography (TEG) and ETP in Sickle Adults Haploidentical PBMC Transplant for Severe Congenital Anemias Transcranial Doppler (TCD) With Transfusions Changing to Hydroxyurea Moderate Dose Hydroxyurea for Secondary Stroke Prevention in Children With Sickle Cell Disease in Sub-Saharan Africa Role of Virtual Reality (VR) in Patients With Sickle Cell Disease (SCD) Allogeneic Genoidentical Stem Cell Transplantation in Children With Sickle-cell Anemia and Cerebral Vasculopathy Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMT CTN 1507) Evaluation of the Safety, Tolerability, Pharmacokinetics (PK) and Effects on Liver Iron Concentration of ICL670 Relative to Deferoxamine(DFO). Sickle Cell Pro-Inflammatory Response to Interval Training Study Comparison of Patient Centered Outcomes for People With Sickle Cell Disease in the Acute Care Setting Neutrophil Extracellular Traps and Sickle Cell Disease A Study of Oral L-citrulline in Sickle Cell Disease LCI-HEM-SCD-ST3P-UP-001: The Sickle Cell Trevor Thompson Transition Project (ST3P-UP Study) Vitamin D for Sickle Cell High-flow Oxygen for Vaso-occlusive Pain Crisis Intermittent Preventive Treatment for Malaria in Patient With Sickle Cell Disease Rifaximin to Modify the Disease Course in Sickle Cell Disease New Hemolysis Parameters in Sickle Cell Disease Phase III Randomized Study of Poloxamer 188 for Vaso-Occlusive Crisis of Sickle Cell Disease Long Term Effects of Erythrocyte Lysis Parent Willingness to Participate in Tobacco Trials in the Pediatric Clinical Setting Study of Clotrimazole and Hydroxyurea in Patients With Sickle Cell Syndromes Blood Flow and Pain Crises in People With Sickle Cell Disease Assessment of Opioid Analgesia in Sickle Cell Topical Sodium Nitrite in Sickle Cell Disease and Leg Ulcers Sparing Conversion to Abnormal TCD (Transcranial Doppler) Elevation (SCATE) Sickle Cell Clinical Research and Intervention Program Shared-Decision Making for Hydroxyurea Inhaled Mometasone to Reduce Painful Episodes in Patients With Sickle Cell Disease A Study Evaluating the Safety and Efficacy of the LentiGlobin BB305 Drug Product in Severe Sickle Cell Disease Apixaban in Patients With Sickle Cell Disease Non-Myeloablative Conditioning and Bone Marrow Transplantation An Extension Study to Further Evaluate the Safety, Tolerability of GBT440 in Patients With Sickle Cell Disease Who Participated in the Study GBT440-001 Parent Educational Program for Children With Sickle Cell Disease Acute Kidney Injury in Patients With Sickle Cell Disease Music Therapy in Sickle Cell Pain Mixed Methods Study Improving Parental Psychosocial Functioning and Early Developmental Outcomes in Children With Sickle Cell Disease Phase I/II Randomized Study of Hydroxyurea With or Without Clotrimazole in Patients With Sickle Cell Anemia BEATS 2: Music Therapy in Sickle Cell Abatacept for GVHD Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor A Safety and Efficacy Study Evaluating CTX001 in Subjects With Severe Sickle Cell Disease Sleep Study in Adult Patients With Major Sickle Cell Disease With Paroxysmal Nocturnal Events Curative Versus Disease-Modifying Therapies in Children With Severe Sickle Cell Disease To Assess Safety, Tolerability and Physiological Effects on Structure and Function of AXA4010 in Subjects With Sickle Cell Disease Expanded Access to Voxelotor for Patients With Sickle Cell Disease Who Have No Alternative Treatment Options Safety Of Rivipansel (GMI-1070) In The Treatment Of One or More Vaso-occlusive Crises In Hospitalized Subjects With Sickle Cell Disease Hemoglobin Desaturation in Sickle Cell Disease Evaluation of Spectra Optia Red Blood Cell Exchange in Sickle Cell Patients Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure Effects of HQK-1001 in Patients With Sickle Cell Disease Patient-Provider Tools to Improve the Transition to Adult Care in Sickle Cell Disease A Study of HQK-1001 in Patients With Sickle Cell Disease Study of Propranolol as Anti-Adhesive Therapy in Sickle Cell Disease (SCD) Pediatric Open-Label Extension of Voxelotor Pulmonary Hypertension in Patients With Sickle Cell Disease in Nigeria Integration of mHEALTH Into the Care of Patients With Sickle Cell Disease to Increase Hydroxyurea Utilization Iron Overload Assesment in Sickle Cell Anemia and Sickle Cell Thalassemia Steroid Treatment for Sickle Cell Pain Crisis Epidemiology and Pathophysiological Mechanisms of HTAP in SS and SC Children in Martinique and Guadeloupe. Heart Arteries and Sickle Cell Disease / Coeur Artères DREpanocytose Epidemiology of Silent and Overt Strokes in Sickle Cell Disease Microvascular and Cardiac Dysfunction in Paroxysmal Nocturnal Hemoglobinuria and Sickle Cell Disease Assessing the Safety of Buprenorphine in People With Sickle Cell Disease Intranasal Ketamine For Pain Control In Patients With Sickle Cell Disease And Vaso-occlusive Episode (VOE) In The PED Tricuspid Regurgitant Jet Velocity as an Independent Marker for Mortality in Sickle Cell Anemia A Blood Stem Cell Transplant for Sickle Cell Disease Central Nervous System Vascular Changes in Adult Sickle Cell Disease and the Effect of Treatment With Simvastatin Efficacy and Safety of Ferriprox® in Patients With Sickle Cell Disease or Other Anemias Evaluation of Knowledge Among Adolescents With Sickle Cell Disease. Dose Escalation Study to Evaluate the Safety, Tolerability, PK and PD of Voxelotor in Patients With SCD Computerized Cognitive Behavioral Therapy Assisted Life Management for Pain in Sickle Cell Disease Single-center Prospective Evaluation of Sickle Cell Patient Care in the CHU Brugmann Emergency Department Long-term Safety and Efficacy of Ferriprox® in Iron Overloaded Patients With Sickle Cell Disease or Other Anemias Management of Severe Acute Malnutrition in SCD, in Northern Nigeria Improving Sickle Cell Disease (SCD) Care Using Web-based Guidelines A Study of Patients Having Pulmonary Hypertension Associated With Sickle Cell Disease and Completing an ASSET Study Implication of the Oxydative Stress in the Pathophysiology of Sickle Cell Anemia: SCD-Haplo: Phase II Study of HLA-Haploidentical SCT for Aggressive SCD A Study of the Safety, Blood Levels and Biological Effects of GBT440 in Healthy Subjects and Subjects With Sickle Cell Disease Study of Methodologies to Measure Blood Flow and Oxygenation in Adults With Sickle Cell Disease Nitric Oxide Therapy for Acute Chest Syndrome in Sickle Cell Disease Children A Stratified Sickle Event Randomized Trial (ASSERT) Decompression Coring Versus Conservative Therapy in Patients With Avascular Necrosis of the Hip Related to Sickle Cell Disease T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias Hydroxyurea and Erythropoietin to Treat Sickle Cell Anemia Functional Neuroimaging of Pain Using EEG and fMRI Study of Deferasirox Relative to Subcutaneous Deferoxamine in Sickle Cell Disease Patients Arginine Therapy for Sickle Cell Disease Pain A SAD/MAD to Assess the Safety, Pharmacokinetics and Pharmacodynamics of FT-4202 in Healthy Volunteers and Sickle Cell Disease Patients Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease Effectiveness of a Computerized Tool (PAINRelieveIt) to Help Manage Pain Related to Sickle Cell Disease ElectroNic Hydroxyurea AdhereNCE: A Strategy to Improve Hydroxyurea Adherence in Patients With Sickle Cell Disease Comparison of Allogeneic Matched Related Haematopoietic Stem Cell Transplantation After a Reduced Intensity Conditioning Regimen With Standard of Care in Adolescents and Adults With Severe Sickle Cell Disease An Extension Study of IMR-687 in Adult Patients With Sickle Cell Anemia Screening Patients With Sickle Cell Disease for Kidney Damage Defibrotide in Sickle Cell Disease-Related Acute Chest Syndrome Androgen Regulation of Priapism in Sickle Cell Disease A Study of the Effect of IW-1701 (Olinciguat), a Stimulator of Soluble Guanylate Cyclase (sGC), on Patients With Sickle Cell Disease (SCD) Adherence to Hydroxyurea in Children With Sickle Cell Anemia iCanCope With Sickle Cell Pain Sickle Cell Anemia and Cerebral Microcirculation : Multimodal Exploration Autologous Bone Marrow Stem Cell Transplantation for Osteonecrosis in Sickle Cell Disease Mesenchymal Stromal Cells for Haplo Hematopoietic Cell Transplantation for Sickle Cell Disease Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell Disease Using Patient-Centered Guidelines in a Technology Platform to Improve Health Care in Adults With Sickle Cell Disease Evaluation of a Training Program for Homozygous Sickle Cell Disease Patients Effect of Exercise With and Without HMB on Body Composition and Muscle Strength in Sickle Cell Anaemia Safety and Efficacy of Gene Therapy of the Sickle Cell Disease by Transplantation of an Autologous CD34+ Enriched Cell Fraction That Contains CD34+ Cells Transduced ex Vivo With the GLOBE1 Lentiviral Vector Expressing the βAS3 Globin Gene in Patients With Sickle Cell Disease (DREPAGLOBE) Impact on the Length of Stay in Incentive Spirometry and Pain in the Decompensation of Sickle Cell Disease: . Transfusion in Sickle Cell Disease: Screening of Sickle Cell Disease Trait in Blood Donors Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Escalating Multiple Oral Doses of AG-348 in Subjects With Stable Sickle Cell Disease A Single Dose Study of the Safety, Blood Levels and Biological Effects of Aes-103 Compared to Placebo in Subjects With Stable Sickle Cell Disease A Pilot Study on Neuroimaging in SCD: Part of The Boston Consortium to Cure Sickle Cell Disease Low-Dose Ketamine Infusion for Children With Sickle Cell Disease-Related Pain The Brigance Assessment Of Individual Neurodevelopment In Young Children With Sickle Cell Disease- 2 Comparing Individualized vs. Weight Based Protocols to Treat VOE in SCD Occlusive Episodes in Sickle Cell Disease Cognitive Rehabilitation in Sickle Cell Disease The Effect of Rivaroxaban in Sickle Cell Disease Muscle Function and Its Biological and Physiological Determinants in Sickle Cell Disease Safety of Single Ascending Doses of CSL889 in Adult Patients With Stable Sickle Cell Disease Sickle Cell Disease and CardiovAscular Risk – Red Cell Exchange Trial (SCD-CARRE) Dose-Finding Study of SC411 in Children With Sickle Cell Disease Sulfadoxine- Pyrimethamine Versus Weekly Chloroquine for Malaria Prevention in Children With Sickle Cell Anemia Decision Aid for Therapeutic Options In Sickle Cell Disease Pathophysiology of Acute Pain in Patients With Sickle Cell Disease Implications of a Paediatrician-psychologist Tandem for Sickle Cell Disease Care and Impact on Cognitive Functioning Vascular Function Intervention Trial in Sickle Cell Disease A Study Evaluating Gene Therapy With BB305 Lentiviral Vector in Sickle Cell Disease Decitabine for High-Risk Sickle Cell Disease Acceptability, Feasibility and Safety of a Yoga Program for Chronic Pain in Sickle Cell Disease Vaporized Cannabis for Chronic Pain Associated With Sickle Cell Disease Effectiveness of Laying-on-of-hands for Sickle Cell Disease Improving Self-Management in Adolescents With Sickle Cell Disease Phase 1/2 Study to Evaluate the Safety, Tolerability and Pharmacokinetics of HQK-1001 Administered Daily in Patients With Sickle Cell Disease Glucose Metabolism in Sickle Cell Disease Sildenafil Therapy for Pulmonary Hypertension and Sickle Cell Disease Improving Disease Knowledge in Adolescents With Sickle Cell Disease Sickle Cell Anemia – A Comparative Study Between Three Ethnical Communities, a Multicenter Study Effect of Atorvastatin on Endothelial Dysfunction and Albuminuria in Sickle Cell Disease Haploidentical Hematopoietic Stem Cell Transplantation (HSCT) for Patients With Severe Sickle Cell Disease Adenosine 2A Agonist Lexiscan in Children and Adults With Sickle Cell Disease Trial of Zileuton CR in Children and Adults With Sickle Cell Disease Efficacy of Vorinostat to Induce Fetal Hemoglobin in Sickle Cell Disease Transfusion in Sickle Cell Disease: Risk Factors for Alloimmunization Pilot Study on the Effects of Intravenous Ketamine on Acute Pain Crisis in Patients With Sickle Cell Disease Effects of Nitric Oxide and Nitroglycerin in Patients With Sickle Cell Anemia Patient Centered Comprehensive Medication Adherence Management System in Patients With Sickle Cell Disease Gene Transfer for Sickle Cell Disease Risk-based Therapy for Sickle Cell Anemia: A Feasibility Study Study to Evaluate the Effect of Voxelotor Administered Orally to Patients With Sickle Cell Disease (GBT_HOPE) Feasibility of a Stress Reduction Intervention Study in Sickle Cell Disease Ketamine as an Adjuvant Therapy for Acute Vaso Occlusive Crisis in Pediatric Patients With Sickle Cell Disease Collect of Cord Blood From Subjects at Risk for Sickle Cell Disease, for the Purpose of Laboratory Research Escalation of Plerixafor for Mobilization of CD34+ Hematopoietic Progenitor Cells and Evaluation of Globin Gene Transfer in Patients With Sickle Cell Disease SACRED A Prospective Research Study to Reduce Stroke in Children With Sickle Cell Anemia A Study to Assess the Safety, Tolerability, and Efficacy of BIVV003 for Autologous Hematopoietic Stem Cell Transplantation in Patients With Severe Sickle Cell Disease Nonmyeloablative Conditioning for Mismatched Hematopoietic Stem Cell Transplantation for Severe Sickle Cell Disease Heart Disease in Sickle Cell Anemia Study of Decitabine and Tetrahydrouridine (THU) in Patients With Sickle Cell Disease A Reduced Toxicity Allogeneic Unrelated Donor Stem Cell Transplantation (SCT) for Severe Sickle Cell Disease Study Exploring the Effect of Crizanlizumab on Kidney Function in Patients With Chronic Kidney Disease Caused by Sickle Cell Disease A Pilot Study of Fecal Microbiome and Neutrophil Cellular Adhesion Molecules in Patients With Sickle Cell Disease (SCD) A Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease A Study of SHP655 (rADAMTS13) in Sickle Cell Disease A Phase Ib Study of NVX-508 in Sickle Cell Disease TRF-1101 Assessment in Sickle Cell Disease Study of Dose Confirmation and Safety of Crizanlizumab in Pediatric Sickle Cell Disease Patients The Spleen in Sickle Cell Anemia and Sickle Cell Thalassemia Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myeloid Chimerism Levels Immunogenicity Study of an Anti-pneumococcal Vaccination Strategy in Patients With Sickle Cells Disease The Implementation of the Automated Erythrocytapheresis in Egyptian Sickle Cell Disease Center Acupuncture for Pain in Sickle Cell Disease Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease Macitentan in Pulmonary Hypertension of Sickle Cell Disease Exhaled Carbon Monoxide as a Marker of Hemolysis in Sickle Cell Disease- an Exploratory Study Hydroxyurea to Prevent Brain Injury in Sickle Cell Disease Study to Assess Safety and Impact of SelG1 With or Without Hydroxyurea Therapy in Sickle Cell Disease Patients With Pain Crises SMYLS: A Self-management Program for Youth Living With Sickle Cell Disease Gum Arabic as Fetal Hemoglobin Agent in Sickle Cell Anemia Pharmacokinetics (PK) of Liquid Hydroxyurea in Pediatric Patients With Sickle Cell Anemia Pain Management in Children and Young Adults With Sickle Cell Disease Clinical Trial to Study the Safety and Tolerability of Memantin Mepha® in Sickle Cell Disease Patients Assessing Function in Pediatric Patients With Sickle Cell Disease Hepcidin Levels in Sickle Cell Disease (SCD) A Study of IMR-687 in Adult Patients With Sickle Cell Anaemia (Homozygous HbSS or Sickle-β0 Thalassemia) European Sickle Cell Disease Cohort – Hydroxyurea Predictors and Outcomes in Patients With Sickle Cell Disease Imatinib for Pain in Sickle Cell Anemia Sildenafil for Treatment of Priapism in Men With Sickle Cell Anemia L-Glutamine Therapy for Sickle Cell Anemia Dronabinol for Pain and Inflammation in Adults Living With Sickle Cell Disease Nitric Oxide and Transfusion Therapy for Sickle Cell Patients With Pulmonary Hypertension L-Glutamine Therapy for Sickle Cell Anemia and Sickle ß0 Thalassemia Zinc for Infection Prevention in Sickle Cell Anemia (ZIPS) Web-MAP Intervention for Youth With Sickle Cell Disease Study to Evaluate the Effect of GBT440 in Pediatrics With Sickle Cell Disease Effect of MitoQ on Platelet Function and Reactive Oxygen Species Generation in Patients With Sickle Cell Anemia iPeer2Peer Program for Youth With Sickle Cell Disease Effect of Ticagrelor vs. Placebo in the Reduction of Vaso-occlusive Crises in Pediatric Patients With Sickle Cell Disease Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients Carbon Monoxide Levels and Sickle Cell Disease Severity Myeloablative Conditioning, Prophylactic Defibrotide and Haplo AlloSCT for Patients With Sickle Cell Disease Ibuprofen and Opioid (Morphine or Diamorphine) for Acute Pain in Sickle Cell Disease – Sickle With Ibuprofen & Morphine Peripheral Blood Stem Cell Collection for Sickle Cell Disease (SCD) Patients Treatment of Sickle Cell Anemia With Stem Cell Transplant Neurovascular Determinants of Cognitive Function in Adults With Sickle Cell Disease Stem Cell Transplantation for Sickle Cell Anemia Zinc Supplementation in Children With Sickle Cell Disease in Western Kenya The Feasibility of the PAINReportIt Guided Relaxation Intervention-Outpatient Endothelial Function in Patients With Sickle Cell Anemia Before and After Sildenafil Evaluating Barriers to Stroke Screening and Prevention in Children With Sickle Cell Disease Codeine in Sickle Cell Disease Autologous Bone Marrow Stem Cells for Chronic Leg Ulcer Treatment in Sickle Cell Disease Safety of Blood Stem Cell Mobilization With Plerixafor in Patients With Sickle Cell Disease Tadalafil for Treatment of Priapism in Men With Sickle Cell Anemia N-Acetylcysteine in Patients With Sickle Cell Disease Atorvastatin Therapy to Improve Endothelial Function in Sickle Cell Disease Stem Cell Transplant in Patients With Severe Sickle Cell Disease Study of Blood Platelets in Sickle Cell Disease Clinical and Laboratory Characteristics of Sickle Cell Anemia Patients Admitted With Fever A Study of the Efficacy and Safety of ICA-17043 (With or Without Hydroxyurea) in Patients With Sickle Cell Anemia. Inhaled Corticosteroid Use to Prevent Acute Chest Syndrome Recurrence in Children Between 1 and 4 With Sickle Cell Disease: a Feasibility Trial Absorption, Metabolism, and Excretion of a Single Dose of Ferriprox® in Patients With Sickle Cell Disease A Safety Study of Eptifibatide in Patients With Sickle Cell Disease A Study Evaluating the Efficacy and Safety of LentiGlobin BB305 Drug Product in Beta-Thalassemia Major and Sickle Cell Disease Laboratory-based Hypnosis Intervention on Pain Responsivity in Adolescents With Sickle Cell Disease The Link Between Anemia and Deficits in Memory and Attention in Individuals With Sickle Cell Disease The Feasibility of the PAINReportIt Guided Relaxation Intervention-INPATIENT Safety and Efficacy of Sodium Nitrite in Sickle Cell Disease Analysis of T-Cell Immune Reconstitution Following Allogeneic Hematopoietic BMT for Severe SCD Hydroxyurea Adherence for Personal Best in Sickle Cell Disease (HABIT): Efficacy Trial Cerebrovascular Reserve Measurements in Sickle Cell Disease Examining the Knowledge, Attitudes, and Beliefs of Sickle Cell Disease Patients, Parents of Patients With Sickle Cell Disease, and Providers Towards the Integration of CRISPR in Clinical Care A New Reagent Assay Examining Natural Parvovirus B19 Infection in Sickle Cell Disease MAP to Provide Access to Crizanlizumab, for Sickle Cell Disease Patients A Pilot Study of Azithromycin Prophylaxis for Acute Chest Syndrome in Sickle Cell Disease Efficacy, Safety Study and Benefit of Alkali Therapy in Sickle Cell Disease Nitric Oxide to Improve Blood Flow in Sickle Cell Disease Risk Clinical Stratification of Sickle Cell Disease in Nigeria, Assessment of Efficacy/Safety of Hydroxyurea Treatment The Efficacy of Jobelyn (Sorghum Bicolor Extract)in the Treatment of Sickle Cell Anemia A Rehabilitation Program in Children With Sickle Cell Disease and Cognitive Deficits: a Pilot Study Hematopoietic Stem Cell Transplant for Sickle Cell Disease Bone Marrow Transplantation vs Standard of Care in Patients With Severe Sickle Cell Disease (BMT CTN 1503) Music Therapy in Sickle Cell Transition Study Evaluation of Hydroxyurea Plus L-arginine or Sildenafil to Treat Sickle Cell Anemia A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease (SCD) Sickle Cell Disease: A Retrospective Chart Review Kidney Function in Sickle Cell Anemia A Multi-Center Study of Riociguat in Patients With Sickle Cell Diseases Sickle Cell Disease Conditioning for Bone Marrow Transplant Study of Beet Juice for Patients With Sickle Cell Anemia Hydroxyurea for the Treatment of Patients With Sickle Cell Anemia Hypnosis to Manage Pain and Symptoms in Patients With Sickle Cell Disease Exercise-induced Pulmonary Hypertension in Patients With Sickle-cell Anemia Kidney Transplantation in Patients With Sickle Cell Disease Simvastatin (Zocor) Therapy in Sickle Cell Disease MUSic Therapy to Improve Quality Of Life in Sickle Cell Disease (MUSIQOLS) Hydroxyurea for Children and Young Adults With Sickle Cell Disease and Pulmonary Hypertension Omega-3 Fatty Acids in Sickle Cell Disease Quantifying the Presence of Lung Disease and Pulmonary Hypertension in Children With Sickle Cell Disease Comparing Acute Pain Management Protocols for Patients With Sickle Cell Disease Vitamin D and Bisphosphonates in the Treatment of Sickle Cell Disease HLA Haploidentical Bone Marrow Transplant in Patients With Severe Sickle Cell Disease Bone Marrow Transplantation in Treating Children With Sickle Cell Disease Stem Cell Transplant in Sickle Cell Disease and Thalassemia Evaluation of Different Dose Regimens of Aes-103 Given for 28 Days to Subjects With Stable Sickle Cell Disease Pain Management Protocol for Pediatric Sickle Cell Disease Clinical and Laboratory Assessment of Iron Overload in Sickle Cell Anemia and Sickle Cell Thalassemia Haploidentical Transplantation With Pre-Transplant Immunosuppressive Therapy for Patients With Sickle Cell Disease A Study of Varespladib Infusion in Subjects With Sickle Cell Disease. Sickle Cell Disease and Endothelial Progenitor Cells (EPCs) Acupuncture for Adults With Sickle Cell Disease (SCD): A Feasibility Study Study to Evaluate the Effect of Ticagrelor Versus Placebo in Reducing Vaso-Occlusive Crises Rate in Pediatric Patients With Sickle Cell Disease. Oxygen Therapy and Pregnancy in Sickle Cell Disease A Study to Evaluate Safety, Pharmacokinetic, and Biological Activity of INCB059872 in Subjects With Sickle Cell Disease Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease A Pilot Study of Chronic Red Blood Cell Transfusion in Sickle Cell Disease-Associated Pulmonary Hypertension Vitamin D Supplementation in Children With Sickle Cell Disease L-Arginine and Sickle Cell Disease Sleep Apnea in Sickle Cell Disease Microvessels and Heart Problems in Sickle Cell Disease Dose-Escalation Study of SCD-101 in Sickle Cell Disease Minimizing Toxicity in HLA-identical Related Donor Transplantation for Children With Sickle Cell Disease Aspirin Prophylaxis in Sickle Cell Disease Sickle Cell Disease: Targeting Alloantibody Formation Reduction; Risk Factors, and Genetics Novel Cardiac Magnetic Resonance Imaging to Define a Unique Restrictive Cardiomyopathy in Sickle Cell Disease DREPAMASSE Study – Evaluation of a Newborn Screening for Sickle Cell Disease by Tandem Mass Spectrometry Study of Hydroxyurea to Treat Sickle Cell Disease Evaluation of the Prevalence of Pulmonary Hypertension in Adult Patients With Sickle Cell Disease A Phase III Safety and Efficacy Study of L-Glutamine to Treat Sickle Cell Disease or Sickle βo-thalassemia A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease A Phase II Trial of Regadenoson in Sickle Cell Anemia Establishment of Functional MRI Imaging Parameters for Use in the Evaluation of Sickle Cell Disease The Role of Endothelin-1 in Sickle Cell Disease Adolescent, Caregiver, and Young Adult Perspectives of the Transition From Pediatric to Adult Care for Sickle Cell Disease: A Preliminary Evaluation of the Sickle Cell Disease Transition Program Long Term Effects of Hydroxyurea Therapy in Children With Sickle Cell Disease Neuropathic Pain in Jamaicans With Sickle Cell Disease Families Taking Control (FTC): Family-based Problem-solving Intervention for Children With Sickle Cell Disease Measurement of Cerebral Blood Flow Using Transcranial Doppler Ultrasound in Children With Sickle Cell Disease Study of a Red Blood Cell Deformability Parameter in Patients With Sickle Cell Disease Sickle Cell Disease Biofluid Chip Technology (SCD BioChip) Sleep Respiratory Disorders Evaluation in Sickle Cell Disease Children SMART Mobile Application Technology Utilization in the Treatment of Sickle Cell Disease Post Day Hospital Discharge The Feasibility of Text Messaging to Assess Secondhand Smoke Exposure Among Youngsters With Cancer or Sickle Cell Disease Study of Efficacy, Safety and Tolerability of ACZ885 (Canakinumab) in Pediatric and Young Adult Patients With Sickle Cell Anemia A Randomized Trial of LOVAZA in Pediatric Sickle Cell Disease (SCD) Stem Cell Transplantation With Identical Donors for Patients With Sickle Cell Disease Study to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell Disease A Sickle CEll Disease ComplicatioN Trial Hydroxyurea in Young Children With Sickle Cell Anemia Contraception in Women With Sickle Cell Disease Efficacy of a Decision Aid for Hydroxyurea in Sickle Cell Disease Sickle Cell Disease, Hemechip Transplantation Using Reduced Intensity Approach for Patients With Sickle Cell Disease From Mismatched Family Donors of Bone Marrow Medication Adherence in Youth With Sickle Cell Disease (SCD) Study of SANGUINATE™ Versus Hydroxyurea in Sickle Cell Disease (SCD) Patients Effect of Simvastatin Treatment on Vaso-occlusive Pain in Sickle Cell Disease Inflammatory Response to Hydroxyurea Therapy in Sickle Cell Disease Blood Sampling for Research Related to Sickle Cell Disease Pediatric -Adult Care Transition Program of Patients With Sickle Cell Disease Assessment of Algorithm-Based Hydroxyurea Dosing on Fetal Hemoglobin Response, Acute Complications, and Organ Function in People With Sickle Cell Disease Qualitative Survey of Potential Exercise Activity in Adults With Sickle Cell Anemia (SCA) Sickle Cell Anemia in an Arab Bedouin Village in the Northern Israel Non-Myeloablative Bone Marrow Transplant for Patients With Sickle Cell Anemia and Other Blood Disorders Hydroxyurea in the Treatment of Sickle Cell Disease Study of Panobinostat (LBH589) in Patients With Sickle Cell Disease Stem Cell Gene Therapy for Sickle Cell Disease Safety, Pharmacokinetic, and Pharmacodynamic Study of NKTT120 in Adult Patients With Stable Sickle Cell Disease (SCD) A Phase 2 Study of the Effects of 6R-BH4 in Subjects With Sickle Cell Disease State Of The Art Functional Imaging In Sickle Cell Disease Study of Intravenous GMI-1070 in Adults With Sickle Cell Disease Survey in a Population of Sickle Cell Disease Patients to Evaluate the Transition Between the Queen Fabiola Children Hospital and the CHU Brugmann Hospital, and the Quality of the Hospital Care Within the CHU Brugmann Hospital. Study of Ventilatory Mechanics in Patients With Sickle Cell Anemia A Study Evaluating the Long-Term Safety of ICA-17043 in Sickle Cell Disease Patients With or Without Hydroxyurea Therapy Ph I/II Study of Allogeneic SCT for Clinically Aggressive Sickle Cell Disease (SCD) Working Memory and School Readiness in Preschool-Aged Children With Sickle Cell Disease MACS Study – Microparticles and Coagulation in Sickle Cell Disease Prevalence of Problematic Use of Equimolar Mixture of Oxygen and Nitrous Oxide and Analgesics in the Sickle-cell Disease Macrolide Therapy to Improve Forced Expiratory Volume in 1 Second in Adults With Sickle Cell Disease Haplo T-Cell Depleted Transplantation in High-Risk Sickle Cell Disease A Brief Laboratory-Based Hypnosis Session for Pain in Sickle Cell Disease Prasugrel Versus Placebo in Adult Sickle Cell Disease Evaluating the Safety and Effectiveness of Bone Marrow Transplants in Children With Sickle Cell Disease (BMT CTN 0601) PK Study of Ticagrelor in Children Aged Less Than 24 Months, With Sickle Cell Disease (HESTIA4) Enhancing Use of Hydroxyurea In Sickle Cell Disease Using Patient Navigators Therapeutic Application of Intravascular Nitrite for Sickle Cell Disease PK and PD Responses to Oral L-Citrulline in Patients With Sickle Cell Disease Sickle Cell Disease (SCD) Decision Aid Evaluation of Purified Poloxamer 188 in Vaso-Occlusive Crisis of Sickle Cell Disease (EPIC) Study of Vitamin D in Children With Sickle Cell Disease Psychometric Evaluation of the IPPAQ in Pediatric Patients With Sickle Cell Disease Hospitalized With Vasoocclusive Pain Haploidentical Stem Cell Transplant for Patients With Sickle Cell Disease and Prior Stroke or Abnormal Transcranial Ultrasound Sickle Cell Anemia WE CARE Improving Emergency Department Management of Adults With Sickle Cell Disease Transfusion Alternatives Pre-Operatively in Sickle Cell Disease (TAPS) Exploring Adherence Monitoring in Sickle Cell Disease Niacin to Improve Blood Flow in People With Sickle Cell Disease HLA-Identical Sibling Donor Bone Marrow Transplantation for Individuals With Severe Sickle Cell Disease Using a Reduced Intensity Conditioning Regimen Propanolol and Red Cell Adhesion Non-asthmatic Children Sickle Cell Disease Plasma DNA and Vascular Remodelling in Patients With Sickle Cell Disease Spectralis HRA+OCT Imaging of the Retina With Autofluorescence in Sickle Cell Disease A Pilot Study of N-acetylcysteine in Patients With Sickle Cell Disease Carbon Monoxide Measurement to Screen for Sickle Cell Disease SALT: Alternative Donor Bone Marrow and Cord Blood Transplantation for High Risk Sickle Cell Disease Safety and Pharmacokinetics of SANGUINATE™ in Sickle Cell Disease (SCD) Patients Cardiovascular Complications of Sickle Cell Disease Bone Marrow Transplantation in Young Adults With Severe Sickle Cell Disease Quantitative MRI for Patients With Sickle Cell Disease Undergoing Hematopoietic Cell Transplant Longitudinal Changes in Exercise Capacity in Children and Young Adults With Sickle Cell Anemia Sickle Cell Disease – Stroke Prevention in Nigeria Trial Exercise Capacity in Pediatric Sickle Cell Anemia A 3-year, Prospective, Non-interventional, Multicenter Registry in Sickle Cell Disease (SCD) Patients Links Between Cognitive Functions and Clinical, Biological and Neuroradiological Outcomes in Adults With Sickle Cell Disease. Molecular Phenotyping of Asthma in Sickle Cell Disease Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia Liver Fibrosis in Sickle Cell Disease Evaluation of the Lung Capillary Blood Volume in Children With Sickle Cell Disease Evaluation of the Hemostatic Potential in Sickle Cell Disease Patients Phase 1 Study of Zoledronic Acid in Sickle Cell Disease Biological, Genetic and Environmental Involved in the Complications of Sickle Cell Disease Community Health Workers and mHealth for Sickle Cell Disease Care Evaluation of Nocturnal Enuresis and Barriers to Treatment Among Pediatric Patients With Sickle Cell Disease Sleep and Pain in Sickle Cell Disease A Study to Assess the Effect of Ticagrelor in Reducing the Number of Days With Pain in Patients With Sickle Cell Disease Gene Transfer for Patients With Sickle Cell Disease Vitamin D3 in Patients With Sickle Cell Disease Collection and Storage of Umbilical Cord Stem Cells for Treatment of Sickle Cell Disease Risk Factors for Allo-immunization in Sickle Cell Disease Added Value of Speckle Tracking in the Evaluation of Patients With Sickle Cell Disease Sickle-cell Disease Registry of the GPOH Microvascular Blood Flow in Sickle Cell Anemia