The SMS Research Roundtable Symposia will be held in conjunction with the Sixth International Family Conference on Smith-Magenis Syndrome, “Building Bridges of Hope,” on September 17-20, 2009. The Research Roundtable commences the conference and fosters the partnership between parents and researchers, which directly supports the PRISMS’ mission. The Research Roundtable gives scientists from around the world a chance to share information and to cultivate research and further partnership. Past roundtables have resulted in significant contributions to the understanding of the symptoms and treatment of SMS.