Acroosteolysis dominant type
Synonyms
4
Overview
Acroosteolysis dominant type is a rare inherited connective tissue disorder characterized by breakdown of bone especially in the ends of the fingers and toes.
Symptoms
- Short stature
- Progressively disappearing bones on ends of fingers
- Progressively disappearing bones on ends of toes
- Crowded carpal bones
- Failure of ossification of cranial sutures
- Thickened cranial vault
- Absent frontal sinus
- Elongated sella turcica
- Progressive basilar impression
- Thick hair
- Straight hair
- Prominent eyelashes
- Prominent eyebrows
- Low-set ears
- Prominent ear lobes
- Broad nose
- Anteverted nostrils
- Premature tooth loss
- Biconcave vertebrae
- Reduced bone mineral density
- Abnormal curvature of the spine
- Skull deformity
- Bone resorption
- Joint laxity
- Reduced bone mass
- Decreased skull ossification
- Hypertelorism
- Long philtrum
- Osteolysis
- Periodontitis
- Short distal phalanx of finge
- Short toe
- Telecanthus
- Wormian bones
Resources
- NIH