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Compassionate use of orphan drug 3,4-Diaminopyridine(DAP) in Treatment of Lambert Eaton
Myasthenic Syndrome (LEMS). 3,4-DAP is used to decrease the muscle weakness associated with
LEMS and hopefully will decrease the need for prednisone and all other therapies that were
previously required to control symptoms. How long a patient will take 3,4 DAP depends upon
if he/she is seeing benefits from the medication or experiencing side effects that will
prevent them from continuation in the study.