PHILADELPHIA-The study of a disease is inherently challenging when patients are few and far between, but doctors at the Perelman School of Medicine at the University of Pennsylvania have reported a new “patient-powered” approach that may help to revolutionize the study of rare diseases. The Penn Medicine researchers, in a...
research News
Cambridge, MA – On the surface, the movement disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, and the cognitive disorder frontotemporal lobar degeneration (FTLD), which underlies frontotemporal dementia, manifest in very different ways. In addition, they are known to primarily affect very different regions of the brain....
BUFFALO, NY – A new research paper was published in Oncoscience on November 10, 2023, entitled, “An immunoinformatics assessment of the cancer testis antigen, DDX53, as a potential early esophageal cancer antigen.” T-lymphocytes have been implicated in facilitating a pro-inflammatory, pro-tumorigenic microenvironment that worsens prognosis for esophageal carcinoma (ESCA). In...
Boston, Mass. – A collaborative project to bring the promise of cell therapy to patients with a deadly form of brain cancer has shown dramatic results among the first patients to receive the novel treatment. In a paper published today in The New England Journal of Medicine, researchers from the...
OAK BROOK, Ill. – Annual breast cancer screening beginning at age 40 and continuing to at least age 79 results in the highest reduction in mortality with minimal risks, according to a new study published today in Radiology, a journal of the Radiological Society of North America (RSNA). Breast cancer...
Los Angeles, California – A new treatment approach that combines a targeted therapy drug with hormone therapy significantly increased the amount of time a person with stage 2 or 3 HR-positive, HER2-negative early breast cancer lives without the cancer returning, according to a new study co-led by UCLA Health...
Melbourne, Australia – A groundbreaking study – the largest of its kind globally – has found children with multiple sclerosis (MS) have better outcomes if treated early and with the same high-efficacy therapies as adults. There are a limited number of therapies approved for children with MS, with only one...
New Brunswick, NJ – The impact of abdominal fat on brain health and cognition is generally more pronounced in middle-aged men at high risk of Alzheimer’s disease as opposed to women, according to researchers at Rutgers Health. In middle-aged individuals with a family history of Alzheimer’s disease, the amount of...
São Paulo, Brazil – A 30-minute walk at moderate intensity temporarily reduced blood pressure in women with rheumatoid arthritis, not only at rest but also under stress. This was the conclusion drawn from a study involving physical and cognitive tests conducted at the University of São Paulo (USP) in Brazil....
Memphis, Tennessee – MYCN is a gene associated with cell proliferation and growth, which is mutated in many types of cancer. Scientists at St. Jude Children’s Research Hospital studying high-risk neuroblastoma found that MYCN plays a role in modifying the cellular state, causing a positive feedback loop that leads to...