Westphal disease
Overview
Westphal disease: A condition that is closely associated with Huntington's disease and is a clinical variant of it.
Symptoms
Rigidity Hypokinesia Bradykinesia Behavioural difficulties Concentration difficulties
Causes
Dystonia 12 - bradykinesia Functional disorders Pallidopyramidal syndrome - bradykinesia Parkinson disease 1 - bradykinesia Parkinson's disease Catatonic syndrome due to other CNS causes Catatonic schizophrenia Neuroleptic induced catatonia
Diagnosis
Diagnosis is based on a characteristic clinical history: progressive chorea and dementia, onset in early middle age (35 to 4), and confirmation of a genetic link. Computed tomography scan and magnetic resonance imaging demonstrate brain atrophy. Molecular genetics may detect the gene for Huntington’s disease in people at risk while they’re still asymptomatic.