Acinic cell carcinoma
Synonyms
1
Overview
A usually slow-growing malignant tumor that that can occur in various parts of the body but is most often found in the pancreas, salivary glands, palate and upper lip. Symptoms are determined by the size and location of the growth.
The disease presents as a slow growing mass, associated with pain or tenderness in 50% of the cases. Often appears pseudoencapsulated.
Symptoms
- Asymptomatic in early stages
- Enlarged salivary gland
- Flank pain
- Nausea
- Vomiting
Diagnosis
These home medical tests may be relevant to Acinic cell carcinoma: * Colon & Rectal Cancer: Home Testing o Home Colorectal Cancer Tests o Home Fecal Occult Bleeding Tests
Prognosis
Prognosis is good for acinic cell carcinoma of the parotid gland, with five-year survival rates approaching is 90%, and 20-year survival exceeding 50%.
The prognosis of an acinic cell carcinoma originating in the lung is much more guarded than cases of this rare histotype occurring in most other organs, but is still considerably better than for other types of lung cancer.
Treatment
- Surgical resection is mainstay of treatment, whenever possible. If tumor is completely removed, post-operative radiation therapy is typically not needed since acinic cell is considered a low-grade histology. Post-operative radiation therapy for acinic cell carcinoma is used if:
- margins are positive
- incomplete resection
- tumor invades beyond gland
- positive lymph nodes
- Neutron beam radiation
- Conventional radiation d) Chemotherapy
Resources
- NIH