Study on the Anti-HPA Antibodies Caused Neonatal Alloimmune Thrombocytopenia in Chinese Pregnant Women

Brief Title

Study on the Anti-HPA Antibodies Caused Neonatal Alloimmune Thrombocytopenia in Chinese Pregnant Women

Official Title

A Multi-center Prospective Cohort Study on the Anti-HPA Antibodies Caused Neonatal Alloimmune Thrombocytopenia in Chinese Pregnant Women

Brief Summary

      This clinical study aims to investigate the anti-HPA antibodies caused neonatal alloimmune
      thrombocytopenia in Chinese pregnant women. The survey and data collect will help form an
      appropriate clinical screening procedure
    



Study Type

Observational


Primary Outcome

The positive rate of anti-HPA antibody

Secondary Outcome

 Antigenic specificity of anti-HPA antibodies

Condition

Neonatal Alloimmune Thrombocytopenia

Intervention

Standard clinical treatment, including intravenous immunoglobulin and/or platelet transfusion

Study Arms / Comparison Groups

 Control Group
Description:  Pregnant women with anti-HPA antibody negative from the same hospital, the same race, and the same gravidity and parity, who are admitted at the same time.

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Procedure

Estimated Enrollment

55497

Start Date

January 2017


Primary Completion Date

December 2019

Eligibility Criteria

        Inclusion Criteria:

          -  12-28 weeks pregnant Chinese women

          -  between Jan 1, 2017 and Dec 31, 2018

        Exclusion Criteria:

          -  Not willing to participate in this study

          -  Plan to terminate pregnancy early
      

Gender

Female

Ages

18 Years - 50 Years

Accepts Healthy Volunteers

Accepts Healthy Volunteers

Contacts

, 0118615178936688, [email protected]



Administrative Informations


NCT ID

NCT02934906

Organization ID

V2.0(20160720)


Responsible Party

Principal Investigator

Study Sponsor

Xinqiao Hospital of Chongqing

Collaborators

 Fourth Military Medical University

Study Sponsor

, , 


Verification Date

October 2016