Prevention of Acute Mountain Sickness by Intermittent Hypoxia

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Brief Title

Prevention of Acute Mountain Sickness by Intermittent Hypoxia

Official Title

Prevention of Acute Mountain Sickness by Sleeping at Simulated Altitude (Normobaric Hypoxia)

Brief Summary

      Acclimatization by mountaineering prior to high altitude sojourns have shown to be effective
      in prevention of acute mountain sickness (AMS).

      The aim of this study is to investigate whether intermittent exposure to normobaric hypoxia
      during sleep is also effective to prevent AMS.
    



Study Type

Interventional


Primary Outcome

incidence of acute mountain sickness

Secondary Outcome

 Sleep quality

Condition

Acute Mountain Sickness

Intervention

Hypoxic Exposure

Study Arms / Comparison Groups

 Normoxia
Description:  Sleeping in normoxia for 14 nights prior to one night at 4500 m

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Other

Estimated Enrollment

75

Start Date

March 2006

Completion Date

July 2007


Eligibility Criteria

        Inclusion Criteria:

          -  healthy

        Exclusion Criteria:

          -  Altitude exposure above 2000 m 8 weeks prior or during the study
      

Gender

Male

Ages

18 Years - 50 Years

Accepts Healthy Volunteers

Accepts Healthy Volunteers

Contacts

Christoph Dehnert, MD, , 

Location Countries

Germany

Location Countries

Germany

Administrative Informations


NCT ID

NCT00559832

Organization ID

039/2006



Study Sponsor

Heidelberg University


Study Sponsor

Christoph Dehnert, MD, Principal Investigator, University Hospital Heidelberg


Verification Date

November 2007