Rhythm Pharmaceuticals Announces Progress in Clinical Development of Setmelanotide for Treatment of Rare Genetic Disorders of Obesity

BOSTON – Rhythm (NASDAQ:RYTM), a biopharmaceutical company aimed at developing and commercializing therapies for the treatment of rare genetic disorders of obesity, announced recent progress in the clinical development of the company’s lead product candidate, setmelanotide, a first-in-class melanocortin-4 receptor (MC4R) agonist. “We are pleased to announce important progress across our clinical… [...]

Audentes Announces Positive Interim Data From First Dose Cohort of ASPIRO, a Phase I/II Clinical Trial of AT132 in Patients With X-Linked Myotubular Myopathy

Audentes Therapeutics (Nasdaq: BOLD), a biotechnology company focused on developing and commercializing gene therapy products for patients living with serious, life-threatening rare diseases, today announced positive interim data from the first dose cohort of ASPIRO, a Phase 1/2 clinical trial of AT132 in patients with X-Linked Myotubular Myopathy (XLMTM). ASPIRO is a… [...]

Pregabalin: a new option for treating epilepsy?

Despite taking medication, many epileptic children still suffer from associated seizures. Now Saudi Arabian researchers might have undertaken the first steps to change this. Epileptic seizures are abnormal electrical discharges in the brain which are usually accompanied by sudden brief episodes of altered or diminished consciousness or convulsions. These do… [...]

Seroquel’s First- and Second-Line Patient Share Has Grown Since Last Year’s Analysis of Prescribing Trends in Bipolar Disorder

WALTHAM, Mass. — Decision Resources, one of the world’s leading research and advisory firms focusing on pharmaceutical and healthcare issues, finds that AstraZeneca Seroquel’s first-line patient share grew two percent since last year’s patient-level claims data analysis of prescribing trends in bipolar disorder. During this same time period other atypicals… [...]

Vaccine preventable diseases: diphtheria

This disease of colder months in temperate areas is practically non-existent in the U.S. due to an aggressive vaccination program for the past several decades. We currently see less than 5 cases of respiratory diphtheria annually. This dangerous respiratory disease is caused by a potent toxin produced by certain strains… [...]

Dramatic outcomes in prostate cancer study

ROCHESTER, Minn. — Two Mayo Clinic patients whose prostate cancer had been considered inoperable are now cancer free thanks in part to an experimental drug therapy that was used in combination with standardized hormone treatment and radiation therapy. The men were participating in a clinical trial of an immunotherapeutic agent… [...]

Herbert Scheinberg, 1919 – 2009

Wilson’s disease is a rare disorder of copper metabolism, an “orphan disease” – a condition so uncommon that its diagnosis and treatment had been neglected. The disease was recognised by the British neurologist Kinnear Wilson in 1912, but a simple means of detecting it did not exist until the 1950s,… [...]

Smallpox: The Death of a Disease

For more than 3000 years, hundreds of millions of people have died or been left permanently scarred or blind by the relentless, incurable disease called smallpox. In 1967, Dr. D.A. Henderson became director of a worldwide campaign to eliminate this disease from the face of the Earth. SMALLPOX—THE DEATH OF… [...]